Headache as the sole presenting symptom of cerebral venous sinuses thrombosis: Subgroup analysis of data from the VENOST study.

Autor:	Duman T; Department of Neurology, Mustafa Kemal University, Hatay, Turkey., Çınar N; Department of Neurology, Maltepe University, İstanbul, Turkey., Uludüz D; Department of Neurology, İstanbul Cerrahpaşa University, İstanbul, Turkey., Domaç FM; Department of Neurologic and Psychiatric Diseases, Erenköy Training and Research Hospital for Neurologic and Psychiatric Diseases, İstanbul, Turkey., Öztürk S; Department of Neurology, Selçuk University, Konya, Turkey., Yayla V; Department of Neurology, Bakırköy Training and Research Hospital, İstanbul, Turkey., Karahan AY; Department of Physical Medicine and Rehabilitation, Uşak University, Uşak, Turkey., Afşar N; Department of Neurology, Acıbadem University, İstanbul, Turkey., Sungur MA; Department of Biostatistics, Düzce University, Düzce, Turkey., Göksu EÖ; Department of Neurology, Antalya Training and Research Hospital, Antalya, Turkey., Yürekli VA; Department of Neurology, Süleyman Demirel University, lsparta, Turkey., Genç H; Department of Neurology, Mersin University, Mersin, Turkey., Utku U; Department of Neurology, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Turkey., Şahin Ş; Department of Neurology, Maltepe University, İstanbul, Turkey., Tekeli H; Department of Neurology, Sultan Abdülhamid Han Training and Research Hospital, İstanbul, Turkey., Tokuç FE; Department of Neurology, Antalya Training and Research Hospital, Antalya, Turkey., Uzuner N; Department of Neurology, Osmangazi University Faculty of Medicine, Eskişehir, Turkey., Şenol MG; Department of Neurology, Sultan Abdülhamid Han Training and Research Hospital, İstanbul, Turkey., Yılmaz A; Department of Neurology, Mersin University, Mersin, Turkey., Gökçe M; Department of Neurology, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Turkey., Demirci S; Department of Neurology, Süleyman Demirel University, lsparta, Turkey., Küsbeci ÖY; Department of Neurology, Bozyaka Education, Research and Training Hospital, İzmir, Turkey., Uzuner GT; Department of Neurology, Osmangazi University Faculty of Medicine, Eskişehir, Turkey., Batur Çağlayan HZ; Department of Neurology, Gazi University Faculty of Medicine, Ankara, Turkey., Açıkgöz M; Department of Neurology, Bülent Ecevit University Faculty of Medicine, Zonguldak, Turkey., Kurucu H; Dementia Research Institute, Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh W1T 7NF, UK., Özdağ MF; Department of Neurology, Sultan Abdülhamid Han Training and Research Hospital, İstanbul, Turkey., Baybaş S; Department of Neurology, Bakirköy Training and Research Hospital for Neurologic and Psychiatric Diseases, İstanbul, Turkey., Ekmekçi H; Department of Neurology, Selçuk University, Konya, Turkey., Çabalar M; Department of Neurology, Bakırköy Training and Research Hospital, İstanbul, Turkey., Yaman M; Department of Neurology Kocatepe University Faculty of Medicine Afyon, Turkey., Bektaş H; Department of Neurology, Atatürk Training and Research Hospital, Ankara, Turkey., Kaplan Y; Department of Neurology, İnonu University Faculty of Medicine, Malatya, Turkey., Göksel BK; Department of Neurology, Başkent University Faculty of Medicine, Adana, Turkey., Milanlioğlu A; Department of Neurology, Yüzüncü Yıl University Faculty of Medicine, Van, Turkey., Örken DN; Department of Neurology, İstanbul Bilim University Faculty of Medicine, İstanbul, Turkey., Aluclu MU; Department of Neurology, Dicle University Faculty of Medicine, Diyarbakır, Turkey., Çolakoğlu S; Department of Neurology, Mustafa Kemal University, Hatay, Turkey., Tüfekçi A; Department of Neurology, Recep Tayyip Erdoğan University Faculty of Medicine, Rize, Turkey., Bakar M; Department of Neurology, Uludag University Faculty of Medicine, Bursa, Turkey., Nazliel B; Department of Neurology, Gazi University Faculty of Medicine, Ankara, Turkey., Tasçılar N; Department of Neurology, Bülent Ecevit University Faculty of Medicine, Zonguldak, Turkey., Göksan B; Department of Neurology, İstanbul Cerrahpaşa University, İstanbul, Turkey., Kozak HH; Department of Neurology, Necmettin Erbakan University Faculty of Medicine, Konya, Turkey., Mısırlı CH; Department of Neurology, Health Sciences University Haydarpaşa Training and Research Hospital, İstanbul, Turkey., Küçükoğlu H; Department of Neurology, Bakirköy Training and Research Hospital for Neurologic and Psychiatric Diseases, İstanbul, Turkey., Midi İ; Department of Neurology, Marmara University Faculty of Medicine, İstanbul, Turkey., Mengüllüoğlu N; Department of Neurology, Eskişehir State Hospital, Eskişehir, Turkey., Aytaç E; Department of Neurology, Ankara Training and Research Hospital, Ankara., Yeşilot N; Department of Neurology, İstanbul University, İstanbul Faculty of Medicine, İstanbul, Turkey., İnce B; Department of Neurology, İstanbul Cerrahpaşa University, İstanbul, Turkey., Yalın OÖ; Department of Neurology, Health Sciences University, İstanbul Training and Research Hospital, İstanbul, Turkey., Güneş T; Department of Neurology, Maltepe State Hospital, İstanbul, Turkey., Oruç S; Department of Neurology Kocatepe University Faculty of Medicine Afyon, Turkey., Demir S; Department of Neurology, Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital, İstanbul, Turkey.
Jazyk:	angličtina
Zdroj:	Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology [Agri] 2021 Jan; Vol. 33 (1), pp. 7-14.
DOI:	10.14744/agri.2020.77698
Abstrakt:	Objectives: Headache is the most common complaint in cerebral venous sinus thrombosis (CVST) and it may sometimes be the only symptom in these patients. This retrospective and prospective study was an investigation of any differences in terms of clinical risk factors, radiological findings, or prognosis in patients with CVST who presented with isolated headache (IH) and cases with other concomitant findings (non-isolated headache [NIH]). Methods: A total of 1144 patients from a multicenter study of cerebral venous sinus thrombosis (VENOST study) were enrolled in this research. The demographic, biochemical, clinical, and radiological aspects of 287 IH cases and 857 NIH cases were compared. Results: There were twice as many women as men in the study group. In the IH group, when gender distribution was evaluated by age group, no statistically significant difference was found. The onset of headache was frequently subacute and chronic in the IH group, but an acute onset was more common in the NIH group. Other neurological findings were observed in 29% of the IH group during follow-up. A previous history of deep, cerebral, or other venous thromboembolism was less common in the IH group than in the NIH group. Transverse sinus involvement was greater in the IH group, whereas sagittal sinus involvement was greater in the NIH group. The presence of a plasminogen activator inhibitor (PAI) mutation was significantly greater in the IH group. Conclusion: IH and CVST should be kept in mind if a patient has subacute or chronic headache. PAI, which has an important role in thrombolytic events, may be a risk factor in CVST. Detailed hematological investigations should be considered. Additional studies are needed.
Databáze:	MEDLINE
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