Continuous positive airway pressure treatment may negatively affect auditory maturation in preterm infants.

Autor: Antinmaa J; Department of Clinical Neurophysiology, Turku University Hospital and University of Turku, Turku, Finland.; Department of Pediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, Finland.; Department of Paediatric Neurology, Tampere University Hospital, Tampere, Finland., Salonen J; Department of Otorhinolaryngology, Turku University Hospital and University of Turku, Turku, Finland., Jääskeläinen SK; Department of Clinical Neurophysiology, Turku University Hospital and University of Turku, Turku, Finland., Kaljonen A; Department of Biostatistics, Faculty of Medicine, University of Turku, Turku, Finland., Lapinleimu H; Department of Pediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, Finland.
Jazyk: angličtina
Zdroj: Acta paediatrica (Oslo, Norway : 1992) [Acta Paediatr] 2021 Nov; Vol. 110 (11), pp. 2976-2983. Date of Electronic Publication: 2021 Jul 18.
DOI: 10.1111/apa.16029
Abstrakt: Aim: Nasal continuous positive airway pressure (CPAP) devices generate loud noise, which might harm auditory function and maturation. The function of auditory pathways can be examined by using brainstem auditory evoked potential (BAEP) and brainstem audiometry (BA) recordings. Our objective was to study whether CPAP treatment during the neonatal period is associated with abnormalities in BAEP and BA recordings.
Methods: Included in this retrospective study were preterm infants (birth weight ≤1500 g and/or gestational age ≤32 weeks) born between 2002 and 2006 with a comprehensive clinical background and follow-up data, including the duration of CPAP treatment (n = 162). BAEP and BA were recorded near the mean corrected age of one month. The following variables from BAEP and BA examinations were analysed: latencies of BAEP components I, III, V, interpeak intervals (IPI) I-V, I-III, III-V (ms), amplitude I and V (µV), amplitude ratio I/V and BA thresholds.
Results: In the adjusted analysis, a longer CPAP treatment leads to longer latencies of BAEP component III (p = 0.01) and V (p = 0.02) in the right ear.
Conclusion: CPAP treatment may impair the auditory maturation and processing mediated via the dominant right ear. The hearing and neurodevelopment of the children who are treated with CPAP should be followed.
(© 2021 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica.)
Databáze: MEDLINE
Externí odkaz: