Anal adenocarcinoma: case report, literature review and comparative survival analysis.

Autor:	Tsay CJ; Medicine, Section of Digestive Diseases, Yale University School of Medicine, New Haven, Connecticut, USA.; Medicine, VA Connecticut Healthcare System-West Haven Campus, West Haven, Connecticut, USA., Pointer T; Yale University Undergraduate Program, New Haven, Connecticut, USA., Chandler JB; Pathology, Yale School of Medicine, New Haven, Connecticut, USA.; Pathology, VA Connecticut Healthcare System-West Haven Campus, West Haven, Connecticut, USA., Nagar AB; Medicine, Section of Digestive Diseases, Yale University School of Medicine, New Haven, Connecticut, USA.; Medicine, VA Connecticut Healthcare System-West Haven Campus, West Haven, Connecticut, USA., Protiva P; Medicine, Section of Digestive Diseases, Yale University School of Medicine, New Haven, Connecticut, USA petr.protiva@yale.edu.; Medicine, VA Connecticut Healthcare System-West Haven Campus, West Haven, Connecticut, USA.
Jazyk:	angličtina
Zdroj:	BMJ open gastroenterology [BMJ Open Gastroenterol] 2021 Jul; Vol. 8 (1).
DOI:	10.1136/bmjgast-2021-000661
Abstrakt:	Introduction: Anal adenocarcinoma is a rare malignancy with a poor prognosis. Methods: We present a case of rare anal adenocarcinoma in a patient with normal screening colonoscopy. Using the Surveillance, Epidemiology and End Result database between 2000 and 2016, we performed survival analysis among individuals>20 years old comparing anal and rectal cancers. Results: Survival analysis showed that anal adenocarcinoma is associated with worse outcomes compared with rectal adenocarcinoma and anal squamous cell carcinoma. Discussion: This case and survival data illustrate the importance of prompt investigation of symptoms irrespective of colorectal cancer screening status with careful attention to examination of the anal area. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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