Serologic evidence of Echinococcus granulosus in slaughterhouses in Pakistan: global alarm for butchers in developing countries.

Autor:	Alvi MA; State Key Laboratory of Veterinary Etiological Biology, National Professional Laboratory of Animal Hydatidosis, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, China. mugheesaizazalvi@gmail.com., Li L; State Key Laboratory of Veterinary Etiological Biology, National Professional Laboratory of Animal Hydatidosis, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, China., Saqib M; Department of Clinical Medicine and Surgery, University of Agriculture, Faisalabad, Pakistan., Ohiolei JA; State Key Laboratory of Veterinary Etiological Biology, National Professional Laboratory of Animal Hydatidosis, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, China., Younas MW; Punjab Livestock and Dairy Development Department, Government of Punjab, Pakistan., Tayyab MH; Department of Clinical Medicine and Surgery, University of Agriculture, Faisalabad, Pakistan., Hassan A; Department of Clinical Medicine and Surgery, University of Agriculture, Faisalabad, Pakistan., Qamar W; Department of Pathobiology, University of Veterinary and Animal Sciences, Lahore (Jhang Campus), Pakistan., Alvi AA; Independent Researcher, Faisalabad, Punjab, Pakistan., Fu BQ; State Key Laboratory of Veterinary Etiological Biology, National Professional Laboratory of Animal Hydatidosis, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, China., Yan HB; State Key Laboratory of Veterinary Etiological Biology, National Professional Laboratory of Animal Hydatidosis, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, China., Jia WZ; State Key Laboratory of Veterinary Etiological Biology, National Professional Laboratory of Animal Hydatidosis, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, China.
Jazyk:	angličtina
Zdroj:	Journal of infection in developing countries [J Infect Dev Ctries] 2021 Jun 30; Vol. 15 (6), pp. 861-869. Date of Electronic Publication: 2021 Jun 30.
DOI:	10.3855/jidc.14029
Abstrakt:	Introduction: Cystic echinococcosis, caused by Echinococcus granulosus, is a neglected zoonosis that affects humans and livestock. This sero-survey was designed for the first time in Pakistan to assess the exposure of butchers to E. granulosus as there was no previous report in the country for this occupational group. Methodology: Blood samples were collected from registered butchers (n = 364) in five different slaughterhouses in Faisalabad and Bahawalnagar Districts. Sera were tested for anti-Echinococcus granulosus IgG with a commercially available ELISA kit (specificity, 100%; sensitivity, 97%). Results: Overall, seroprevalence was 9.61% (35/364). Butchers >30 years of age (10.34%), those involved in small ruminants butchery (11.70%), >10 years' experience (10.04%), formal education level up to middle standard (10.28%), contact with dogs (12.71%), improper/unhygienic disposal of dog feces (11.87%), and those unaware of the consequences of eating with unwashed hands (13.80%) were more seropositive with significant statistical differences (p < 0.05). Variables like previous cyst encounter, no knowledge of zoonoses and/or cystic echinococcosis, living in rural areas and the presence of stray/feral dogs in surroundings did not show any significant association (p > 0.05) with seroprevalence in butchers. The binary logistic regression model also showed a statistically significant relationship (p < 0.05) for all risk factors found statistically significant (p < 0.05) in the univariate analysis. Conclusions: This study shows high prevalence of cystic echinococcosis among butchers in Pakistan and underscores the need for educating native slaughterhouse personnel on cystic echinococcosis. It also serves as a global warning, especially in developing countries. Competing Interests: No Conflict of Interest is declared (Copyright (c) 2021 Mughees Aizaz Alvi, Li Li, Muhammad Saqib, John Asekhaen Ohiolei, Muhammad Waqar Younas, Muhammad Haleem Tayyab, Ali Hassan, Warda Qamar, Anum Aizaz Alvi, Bao-Quan Fu, Hong-Bin Yan, Wan-Zhong Jia.)
Databáze:	MEDLINE
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