Analysis of left ventricular function, left ventricular outflow tract and aortic valve area using computed tomography: Influence of reconstruction parameters on measurement accuracy.

Autor: Hell MM; Department of Cardiology, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany.; Department of Cardiology, University Medical Center Mainz, Johannes Gutenberg University, Mainz, Germany., Steinmann B; Department of Cardiology, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany., Scherkamp T; Department of Cardiology, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany., Arnold MB; Department of Cardiology, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany., Achenbach S; Department of Cardiology, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany., Marwan M; Department of Cardiology, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany.
Jazyk: angličtina
Zdroj: The British journal of radiology [Br J Radiol] 2021 Aug 01; Vol. 94 (1124), pp. 20201306. Date of Electronic Publication: 2021 Jul 08.
DOI: 10.1259/bjr.20201306
Abstrakt: Objectives: Computed tomography (CT) allows reproducible assessment of left ventricular (LV) function, left ventricular outflow tract area (LVOT area ) and aortic valve area (AVA). We evaluated the influence of image reconstruction parameters on these measurements.
Methods: We analyzed 45 contrast-enhanced, retrospectively ECG-gated CT datasets acquired on a third-generation dual source system. A standard filtered-back-projection data set (20 cardiac phases (5% steps, 0-95%), 0.6-mm-slice thickness, 512 × 512 matrix) and eight reconstructions with modified slice thickness (1-8 mm), number of cardiac phases (5, 10), matrix size (256×256) and an iterative reconstruction (IR) algorithm were obtained. LV parameters (ejection fraction (EF), stroke volume (SV), end-diastolic (EDV), end-systolic volumes (ESV)), LVOT area and AVA were assessed.
Results: Differences in LV parameters, LVOT area and AVA, were only minimal between standard reconstructions and those with modified matrix size, IR algorithm and ≤2 mm slice thickness, while reconstructions with 8-mm slice thickness significantly overestimated SV ( p < 0.001) and EDV ( p = 0.016). AVA planimetry in reconstructions with ≥5 mm slice thickness was not feasible in 56% of patients. A decrease in the number of reconstructed phases (10 or 5) underestimated EF, SV, EDV, LVOT area and AVA and overestimated ESV.
Conclusions: Modifications of reconstruction parameters (except a slice thickness ≤2 mm) have only a marginal effect on LV, LVOT area and AVA assessment. However, a reduced number of reconstructions per cardiac cycle may significantly influence measurements.
Advances in Knowledge: Substantial modifications in number of reconstructions per cardiac cycle significantly affect the assessment of LV function, LVOT area and AVA also in modern CT scanners.
Databáze: MEDLINE
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