Autor: |
Arapov OV, Alferova OF, Levocheskaia EI, Krasil'nikov II |
Jazyk: |
ruština |
Zdroj: |
Radiobiologiia [Radiobiologiia] 1987 Nov-Dec; Vol. 27 (6), pp. 843-6. |
Abstrakt: |
As was shown in experiments with rats and mice some acyl hydrazones have a pronounced radioprotective effect. The protective efficiency makes 40-55 per cent with the preparation doses of 1-10 mg/kg. The toxicity of hydrazones is 2 g/kg which is lower, than that of the known sulfur-containing agents and substituted indolylalkylamines. The radio-protective efficiency of the drug depends on its complex-forming ability. |
Databáze: |
MEDLINE |
Externí odkaz: |
|