Isolated renal mucormycosis presenting with bilateral renal artery thrombosis: a case report.

Autor: Saneesh PS; Deapartment of Radiology, Aster MIMS, Kannur, Kerala India., Yelamanchi R; Department of Surgery, Ward 17, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, 110001 India., Pilllai S; Department of Pathology, Carithas Hospital, Kottayam, Kerala India.
Jazyk: angličtina
Zdroj: African journal of urology : the official journal of the Pan African Urological Surgeons' Association (PAUSA) [Afr J Urol] 2021; Vol. 27 (1), pp. 86. Date of Electronic Publication: 2021 Jun 30.
DOI: 10.1186/s12301-021-00193-3
Abstrakt: Background: Mucormycosis is a rare infection caused by the fungus belonging to the order Mucorales . Mucormycosis predominantly affects immunocompromised individuals such as people with acquired immunodeficiency syndrome, blood malignancies, organ transplant, etc. Involvement of the kidneys usually occurs as a result of disseminated mucormycosis. We report a very rare case of isolated renal mucormycosis in an immunocompetant individual without any prior comorbidities who had an unusual presentation of mucormycosis.
Case Presentation: A 17-year-old male student had presented to our emergency department with complaints of bilateral loin pain and fever for 10 days. There was no urine output for 2 days. Patient was in sepsis with acute kidney injury. A Doppler ultrasound of the abdomen revealed bilateral enlarged kidneys with absent blood flow in the renal vasculature. Dialysis was done, and patient was started on intravenous antibiotics. Patient was investigated for thrombophilia, the test results of which were normal. Sickle cell test was negative. Immunodeficiency screening was negative. Contrast-enhanced computed tomography revealed bilateral enlarged kidneys with bilateral renal artery thrombosis and mild ascitis. CT-guided renal biopsy was performed in the same sitting which revealed fungal hyphae in the background of necrotic glomeruli. Patient was started on liposomal amphotericin B with renal replacement therapy. However, patient deteriorated and succumbed to sepsis on the 4th day of admission.
Conclusion: Isolated renal mucormycosis with bilateral renal artery thrombosis is a very rare clinical scenario with high mortality. One must have a high degree of suspicion to diagnose renal mucormycosis at an early stage.
Competing Interests: Competing interestsAuthors declare that they have no competing interests.
(© The Author(s) 2021.)
Databáze: MEDLINE
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