Does Raising the Arms Modify Head Tremor Severity in Cervical Dystonia?

Autor:	Cisneros E; Institute for Neural Computation, University of California, San Diego, La Jolla, CA, USA., Vu JP; Institute for Neural Computation, University of California, San Diego, La Jolla, CA, USA., Lee HY; Institute for Neural Computation, University of California, San Diego, La Jolla, CA, USA., Chen Q; Institute for Neural Computation, University of California, San Diego, La Jolla, CA, USA., Benadof CN; Institute for Neural Computation, University of California, San Diego, La Jolla, CA, USA., Zhang Z; Institute for Neural Computation, University of California, San Diego, La Jolla, CA, USA., Pettitt EA; Institute for Neural Computation, University of California, San Diego, La Jolla, CA, USA., Joshi SK; Institute for Neural Computation, University of California, San Diego, La Jolla, CA, USA., Barbano RL; Department of Neurology, University of Rochester, Rochester, NY, USA., Jankovic J; Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, TX, USA., Jinnah HA; Departments of Neurology and Human Genetics, Emory University, Atlanta, GA, USA., Perlmutter JS; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Departments of Radiology, Neuroscience, Physical Therapy, and Occupational Therapy, Washington University School of Medicine, St. Louis, MO, USA., Berman BD; Department of Neurology, Virginia Commonwealth University, Richmond, VA, USA., Mahajan A; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA., Goetz CG; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA., Stebbins GT; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA., Comella CL; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA., Peterson DA; Institute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.; Computational Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.
Jazyk:	angličtina
Zdroj:	Tremor and other hyperkinetic movements (New York, N.Y.) [Tremor Other Hyperkinet Mov (N Y)] 2021 Jun 23; Vol. 11, pp. 21. Date of Electronic Publication: 2021 Jun 23.
DOI:	10.5334/tohm.623
Abstrakt:	Background: A defining characteristic of dystonia is its position-dependence. In cervical dystonia (CD), sensory tricks ameliorate head tremor (HT). But it remains unknown whether raising the arms alone has the same impact. Methods: We analyzed data collected from patients enrolled by the Dystonia Coalition. For 120 patients with HT, we assessed how raising their arms without touching their head changed their HT severity. Results: Forty-eight out of 120 patients exhibited changes in HT severity when raising their arms. These patients were more likely to exhibit decreases in HT severity (N = 35) than increases (N = 13, χ 2 (1, N = 48) = 10.1, p = 0.002). Demographic factors and sensory trick efficacy were not significant predictors of whether HT severity changed when raising their arms. Discussion: Raising the arms without touching the head is a posture that can reduce HT severity in some CD patients. Our results extend the concept of position-dependent motor symptoms in CD to include the position of the arms. Highlights: Head tremor (HT) is a prevalent symptom of cervical dystonia (CD) that can often be disabling. This study demonstrates that raising the arms without touching the head is a posture that can reduce HT severity in some CD patients. Our findings also identify a novel form of position-dependence in CD. Competing Interests: The authors have no competing interests to declare. (Copyright: © 2021 The Author(s).)
Databáze:	MEDLINE
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