Association between periodontitis and vitamin D status: A case-control study.

Autor: Alzahrani AAH; Dental Health Department, Faculty of Applied Medical Sciences, Albaha University, Albaha, Saudi Arabia., Alharbi RA; Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Albaha University, Albaha, Saudi Arabia., Alzahrani MSA; Endodontics Department, Faculty of Clinical Dentistry, Albaha University, Albaha, Saudi Arabia., Sindi MA; Department of Primary Health Care Administration, Public Health Directorate, 26522 Taif, Saudi Arabia., Shamlan G; Department of Food Science and Nutrition, College of Food and Agriculture Sciences, King Saud University, Riyadh 11362, Saudi Arabia., Alzahrani FA; Dental Health Specialist, Department of Medical Services General Administration, Public Security, The Saudi Ministry of Interior, Riyadh, Saudi Arabia., Albanghali MA; Public Health Department, Faculty of Applied Medical Sciences, Albaha University, Albaha, Saudi Arabia., Sindi AAA; Department of Basic Medical Science, Faculty of Applied Medical Sciences, Albaha University, 65779 Albaha, Saudi Arabia.
Jazyk: angličtina
Zdroj: Saudi journal of biological sciences [Saudi J Biol Sci] 2021 Jul; Vol. 28 (7), pp. 4016-4021. Date of Electronic Publication: 2021 Apr 20.
DOI: 10.1016/j.sjbs.2021.04.006
Abstrakt: Vitamin D deficiency and periodontitis are commonly prevalent among Saudi adults. However, the association between periodontitis and vitamin D status has not been well documented. This study aims to examine the association between periodontitis and vitamin D status among adults in the Albaha region of Saudi Arabia. A case-control study of 123 Saudi adults was conducted; 60 had severe or moderate periodontitis, and 63 were periodontally healthy. Data was collected by an online self-reported sociodemographic questionnaire. All participants then underwent a full periodontal examination. Blood samples were also provided to assess participants' vitamin D statuses through serum levels of 25-hydroxyvitamin D (25(OH)D). A total of 60 cases and 63 controls matched for BMI (30.2 ± 4.86 kg/m 2 ), age (40.01 ± 7.73 years), and sex (46.3% and 53.7% male and female, respectively) participated in the study. Mean levels of 25(OH)D were significantly lower in periodontitis participants than in controls (25.03 ± 8.55 ng/ml, 29.19 ± 12.82 ng/ml, p  = 0.037, respectively). Lower odds of periodontitis were detected per unit of 25(OH)D level (OR 0.964, 95% CI; 0.931-0.999, p  = 0.043). In conclusion, periodontitis is significantly associated with deficient and insufficient levels of vitamin D among Saudi adults in the Albaha region. Future longitudinal research with a larger sample size may be suggested to confirm these results.
Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Databáze: MEDLINE