Gender differences in the blood glucose type 2 diabetes patients with combination rapid and long acting insulin therapy.

Autor:	Ratri DMN; Department of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, East Java, Indonesia.; Department of Pharmacy, Universitas Airlangga Hospital, Surabaya, East Java, Indonesia., Puspitasari AD; Department of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, East Java, Indonesia.; Department of Pharmacy, Universitas Airlangga Hospital, Surabaya, East Java, Indonesia., Nugroho CW; Internal Medicine Department, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia.; Internal Medicine Department, Universitas Airlangga Hospital, Surabaya, East Java, Indonesia., Suprapti B; Department of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, East Java, Indonesia.; Department of Pharmacy, Universitas Airlangga Hospital, Surabaya, East Java, Indonesia., Suharjono; Department of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, East Java, Indonesia., Alderman CP; Faculty of Pharmacy, Universitas Airlangga, Surabaya, East Java, Indonesia.; School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia.
Jazyk:	angličtina
Zdroj:	Journal of basic and clinical physiology and pharmacology [J Basic Clin Physiol Pharmacol] 2021 Jun 25; Vol. 32 (4), pp. 567-570. Date of Electronic Publication: 2021 Jun 25.
DOI:	10.1515/jbcpp-2020-0463
Abstrakt:	Objectives: Previous research suggests that there may be intergender differences in the profile of glycemic control achievable during the treatment of type 2 diabetes mellitus. This preliminary study was conducted to determine differences in glycemic outcomes in type 2 diabetes mellitus patients amongst men and women in an Indonesian hospital. Methods: The study was conducted at the outpatient internal medicine polyclinic of Universitas Airlangga Teaching Hospital Surabaya. This observational prospective cohort study examining outcomes for 64 patients (32 men and 32 women) treated with insulin therapy. The primary outcome measure was the extent to which subjects achieved concordance with the target blood glucose parameters based on the American Diabetes Association (ADA) guidance. Results: After 3 months of combination basal-bolus insulin treatment, the proportion of subjects who had fasting blood glucose values in the target range did not increase for either gender. For women, there was a significantly higher proportion of subjects who achieved a postprandial glucose value within the target range (p=0.04). Conclusions: In this study, patients achieved postprandial glycemic outcomes for women but not men. More research is required to elucidate the possible intergender difference in results for subjects treated with basal-bolus insulin for type 2 diabetes mellitus. (© 2021 Walter de Gruyter GmbH, Berlin/Boston.)
Databáze:	MEDLINE
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