Mandibulectomy Reconstruction with Pectoralis Major Island Flap Associated with Primary Reconstruction Plate for Mandibular Medication-Related Osteonecrosis.

Autor: Ciobanu GA; Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, Romania., Gheorghiţă MI; Department of Oral and Maxillo-Facial Surgery, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, Romania., Petrescu OM; Department of Oral and Maxillo-Facial Surgery, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, Romania., Popescu SM; Department of Oral Rehabilitation and Medical and Surgical Emergencies, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, Romania., Staicu IE; Department of Orthodontics, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, Romania.
Jazyk: angličtina
Zdroj: Current health sciences journal [Curr Health Sci J] 2021 Jan-Mar; Vol. 47 (1), pp. 117-122. Date of Electronic Publication: 2021 Mar 31.
DOI: 10.12865/CHSJ.47.01.19
Abstrakt: A bimaxillary edentulous male patient, aged 67 years, diagnosed with prostate cancer who underwent intravenous bisphosphonates treatment (zoledronic acid) for about one year presented with pain in the anterior mandibular arch, with exposed necrotic bone, and was diagnosed with stage 2 medication-related osteonecrosis of the jaw (MRONJ). MRONJ is the development of bone necrosis in the oral cavity as an adverse reaction in patients treated with antiresorptive and antiangiogenic medication, without radiation therapy to the head and neck. This persistent bone necrosis does not always respond to standard treatments. The reconstruction technique with pectoralis major flap, at a distance, associated with the primary reconstruction plate, was an effective treatment modality for the treatment of large osteonecrosis noncompliant with conservatory treatments. Through this technique, the morpho-functionality of the jaw can be restored almost completely.
Competing Interests: None to declare.
(Copyright © 2014, Medical University Publishing House Craiova.)
Databáze: MEDLINE
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