Alprostadil associated with low molecular weight heparin to treat limb ischemia caused by SARS-CoV2.
| Autor: | Manhanelli MAB; Pontifícia Universidade Católica de São Paulo - PUC-SP, Sorocaba, SP, Brasil.; Conjunto Hospitalar de Sorocaba, Sorocaba, SP, Brasil., Duarte EG; Hospital Santa Mônica, Cirurgia Vascular e Endovascular, Vila Velha, ES, Brasil.; Universidade Vila Velha - UVV, Vila Velha, ES, Brasil., Mariuba JVO; Pontifícia Universidade Católica de São Paulo - PUC-SP, Sorocaba, SP, Brasil., Linardi F; Pontifícia Universidade Católica de São Paulo - PUC-SP, Sorocaba, SP, Brasil.; Conjunto Hospitalar de Sorocaba, Sorocaba, SP, Brasil., Costa JA; Pontifícia Universidade Católica de São Paulo - PUC-SP, Sorocaba, SP, Brasil., Gali JC; Pontifícia Universidade Católica de São Paulo - PUC-SP, Sorocaba, SP, Brasil., Yoshida WB; Universidade Estadual Paulista 'Júlio de Mesquita Filho' - UNESP, Botucatu, SP, Brasil., Gali JC; JJMED, Sorocaba, SP, Brasil. |
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| Jazyk: | angličtina |
| Zdroj: | Jornal vascular brasileiro [J Vasc Bras] 2020 Nov 30; Vol. 19, pp. e20200072. Date of Electronic Publication: 2020 Nov 30. |
| DOI: | 10.1590/1677-5449.200072 |
| Abstrakt: | The current coronavirus pandemic has already taken a great toll globally, causing massive morbidity and mortality. One of its severe forms is a thrombophilic state that can damage several systems. This article reports the case of 60-year-old female patient who presented with mild flu symptoms, which turned out to be a SARS-CoV2 infection, and ended up developing arterial thrombosis with limb ischemia in a private care hospital in Sorocaba, São Paulo, Brazil. Considering this progression, we decided to intervene with low molecular weight heparin and Alprostadil, achieving a good clinical outcome. Our description aims to identify key points and clinical signs that offer evidence of the therapeutic window and a treatment option for coagulatory presentations of COVID-19. Competing Interests: Conflicts of interest: No conflicts of interest declared concerning the publication of this article. |
| Databáze: | MEDLINE |
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