Bacterial Infections in Humans and Nonhuman Primates from Africa: Expanding the Knowledge.

Autor:	Medkour H; IHU Méditerranée Infection, Marseille, France.; Aix Marseille Université, IRD, AP-HM, Microbes, MEPHI, Marseille, France.; PADESCA Laboratory, Veterinary Science Institute, University Constantine, El Khroub, Algeria., Amona I; IHU Méditerranée Infection, Marseille, France.; Aix-Marseille Université, IRD, AP-HM, SSA, VITROME, Marseille, France.; Faculté des Sciences et Techniques, Université Marien NGOUABI, Brazzaville, Republic of the Congo., Akiana J; Laboratoire National de Santé Publique, Brazzaville, Republic of the Congo., Laidoudi Y; IHU Méditerranée Infection, Marseille, France.; Aix Marseille Université, IRD, AP-HM, Microbes, MEPHI, Marseille, France.; PADESCA Laboratory, Veterinary Science Institute, University Constantine, El Khroub, Algeria., Davoust B; IHU Méditerranée Infection, Marseille, France.; Aix Marseille Université, IRD, AP-HM, Microbes, MEPHI, Marseille, France., Bitam I; Aix-Marseille Université, IRD, AP-HM, SSA, VITROME, Marseille, France.; Superior School of Food Sciences and Food Industries, Algiers, Algeria., Lafri I; Aix-Marseille Université, IRD, AP-HM, SSA, VITROME, Marseille, France.; Institute of Veterinary Sciences, University of Blida 1, Blida, Algeria.; Laboratory of Biotechnology related to Animal Reproduction (LBRA), University of Blida 1, Blida, Algeria., Levasseur A; IHU Méditerranée Infection, Marseille, France.; Aix Marseille Université, IRD, AP-HM, Microbes, MEPHI, Marseille, France., Diatta G; Aix-Marseille Université, IRD, AP-HM, SSA, VITROME, Marseille, France.; IRD VITROME, Dakar, Senegal., Sokhna C; IHU Méditerranée Infection, Marseille, France.; Aix-Marseille Université, IRD, AP-HM, SSA, VITROME, Marseille, France.; IRD VITROME, Dakar, Senegal., Hernandez-Aguilar RA; IRD VITROME, Dakar, Senegal.; Department of Social Psychology and Quantitative Psychology, Faculty of Psychology, University of Barcelona, Barcelona, Spain., Barciela A; Jane Goodall Institute Spain and Senegal, Dindefelo Biological Station, Dindefelo, Kedougou, Senegal., Gorsane S; Direction interarmées du Service de santé des armées des Forces Françaises stationnées à Djibouti., Banga-Mboko H; Ecole Nationale d'Agronomie et de Foresterie, Université Marien Ngouabi, Brazzaville, Republic of the Congo., Raoult D; IHU Méditerranée Infection, Marseille, France.; Aix Marseille Université, IRD, AP-HM, Microbes, MEPHI, Marseille, France., Fenollar F; IHU Méditerranée Infection, Marseille, France.; Aix-Marseille Université, IRD, AP-HM, SSA, VITROME, Marseille, France., Mediannikov O; IHU Méditerranée Infection, Marseille, France.; Aix Marseille Université, IRD, AP-HM, Microbes, MEPHI, Marseille, France.
Jazyk:	angličtina
Zdroj:	The Yale journal of biology and medicine [Yale J Biol Med] 2021 Jun 30; Vol. 94 (2), pp. 227-248. Date of Electronic Publication: 2021 Jun 30 (Print Publication: 2021).
Abstrakt:	The close phylogenetic relationship between humans and other primates creates exceptionally high potential for pathogen exchange. The surveillance of pathogens in primates plays an important role in anticipating possible outbreaks. In this study, we conducted a molecular investigation of pathogenic bacteria in feces from African nonhuman primates (NHPs). We also investigated the pathogens shared by the human population and gorillas living in the same territory in the Republic of Congo. In total, 93% of NHPs (n=176) and 95% (n=38) of humans were found to carry at least one bacterium. Non- pallidum Treponema spp. (including T. succinifaciens , T. berlinense , and several potential new species) were recovered from stools of 70% of great apes, 88% of monkeys, and 79% of humans. Non- tuberculosis Mycobacterium spp. were also common in almost all NHP species as well as in humans. In addition, Acinetobacter spp., members of the primate gut microbiota, were mainly prevalent in human and gorilla. Pathogenic Leptospira spp. were highly present in humans (82%) and gorillas (66%) stool samples in Congo, but were absent in the other NHPs, therefore suggesting a possible gorillas-humans exchange. Particular attention will be necessary for enteropathogenic bacteria detected in humans such as Helicobacter pylori , Salmonella spp. (including S. typhi/paratyphi ), Staphyloccocus aureus , and Tropheryma whipplei , some of which were also present in gorillas in the same territory ( S. aureus and T. whipplei ). This study enhances our knowledge of pathogenic bacteria that threaten African NHPs and humans by using a non-invasive sampling technique. Contact between humans and NHPs results in an exchange of pathogens. Ongoing surveillance, prevention, and treatment strategies alone will limit the spread of these infectious agents. (Copyright ©2021, Yale Journal of Biology and Medicine.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu