| Autor: |
Hasan T; Faculty of Medicine and Health, The University of Sydney, Sydney 2006, Australia.; The Woolcock Institute of Medical Research, Glebe 2037, Australia., Pham TN; National Hospital for Tropical Diseases, Hanoi 12319, Vietnam., Nguyen TA; The Woolcock Institute of Medical Research, Glebe 2037, Australia., Le HTT; The Woolcock Institute of Medical Research, Glebe 2037, Australia., Van Le D; National Hospital for Tropical Diseases, Hanoi 12319, Vietnam., Dang TT; National Hospital for Tropical Diseases, Hanoi 12319, Vietnam., Van TD; National Hospital for Tropical Diseases, Hanoi 12319, Vietnam., Pham YN; The Woolcock Institute of Medical Research, Glebe 2037, Australia., Nguyen HV; The Woolcock Institute of Medical Research, Glebe 2037, Australia., Tran GL; The Woolcock Institute of Medical Research, Glebe 2037, Australia., Nguyen VTC; The Woolcock Institute of Medical Research, Glebe 2037, Australia., Nguyen TT; The Woolcock Institute of Medical Research, Glebe 2037, Australia., Truong VQ; Hanoi Center for Disease Control (CDC), Hanoi 11512, Vietnam., Dao TH; Hanoi Center for Disease Control (CDC), Hanoi 11512, Vietnam., Le CT; Da Nang Centre for Disease Control, Da Nang City 50213, Vietnam., Truong NT; Da Nang Centre for Disease Control, Da Nang City 50213, Vietnam., Vo HT; Quang Nam Centre for Disease Control, Quang Nam 51108, Vietnam., Le PT; Da Nang Lung Hospital, Da Nang City 50606, Vietnam., Nguyen TT; Quang Nam Pham Ngoc Thach Hospital, Quang Nam 51110, Vietnam., Van Luu V; Quang Nam Pham Ngoc Thach Hospital, Quang Nam 51110, Vietnam., Nguyen VD; Hoa Vang District Health Center, Da Nang City 50807, Vietnam., Toelle BG; Faculty of Medicine and Health, The University of Sydney, Sydney 2006, Australia.; The Woolcock Institute of Medical Research, Glebe 2037, Australia.; Sydney Local Health District, Sydney 2050, Australia., Marks GB; The Woolcock Institute of Medical Research, Glebe 2037, Australia.; South Western Sydney Clinical School, The University of New South Wales, Liverpool 2170, Australia., Fox GJ; Faculty of Medicine and Health, The University of Sydney, Sydney 2006, Australia.; The Woolcock Institute of Medical Research, Glebe 2037, Australia. |
| Abstrakt: |
As a response to the coronavirus disease 2019 (COVID-19) pandemic, Vietnam enforced strict quarantine, contact tracing and physical distancing policies resulting in one of the lowest numbers of individuals infected with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) globally. This study aimed to determine the prevalence of SARS-CoV-2 antibody positivity among high-risk populations in Vietnam. A prevalence survey was undertaken within four communities in Vietnam, where at least two COVID-19 cases had been confirmed. Participants were classified according to the location of exposure: household contacts, close contacts, community members, and healthcare workers (HCWs) responsible for treating COVID-19 cases. Participants completed a baseline questionnaire and SARS-CoV-2 IgG antibodies were quantified using a commercial assay. A total of 3049 community members and 149 health care workers consented to the study. Among 13 individuals who were seropositive (0.4%), five household contacts (5/27, 18.5%), one close contact (1/53, 1.9%), and seven community members (7/2954, 0.2%) had detectable SARS-CoV-2 antibodies. All HCWs were negative for SARS-CoV-2 antibodies. Participants were tested a median of 15.1 (interquartile range from 14.9 to 15.2) weeks after exposure. Our study found a low prevalence of SARS-CoV-2 antibodies in high-risk communities and healthcare workers in communities in Vietnam with known COVID-19 cases. |
