Systematic review and meta-analyses of vitamin E (alpha-tocopherol) supplementation and blood lipid parameters in patients with diabetes mellitus.

Autor: Mohammad A; Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400, Serdang, Selangor, Malaysia. Electronic address: abolfathi.m54@gmail.com., Falahi E; Nutritional Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran. Electronic address: e_falahi@yahoo.com., Barakatun-Nisak MY; Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400, Serdang, Selangor, Malaysia; Research Centre of Excellence for NCD (Nutrition and Non-communicable Diseases), Universiti Putra Malaysia, UPM, 43400, Serdang, Selangor, Malaysia. Electronic address: bnisak@upm.edu.my., Hanipah ZN; Department of Surgery, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400, Serdang, Selangor, Malaysia. Electronic address: n_baidah@upm.edu.my., Redzwan SM; Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400, Serdang, Selangor, Malaysia. Electronic address: mohdredzwan@upm.edu.my., Yusof LM; Department of Companion Animal Medicine and Surgery, Faculty of Veterinary Medicine, Universiti Putra Malaysia, UPM, 43400, Serdang, Selangor, Malaysia. Electronic address: myloqman@gmail.com., Gheitasvand M; Department of Pathology, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran. Electronic address: Dr.gheitasvand@yahoo.com., Rezaie F; Department of Pathology, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran. Electronic address: f.rezaiee80@gmail.com.
Jazyk: angličtina
Zdroj: Diabetes & metabolic syndrome [Diabetes Metab Syndr] 2021 Jul-Aug; Vol. 15 (4), pp. 102158. Date of Electronic Publication: 2021 May 31.
DOI: 10.1016/j.dsx.2021.05.031
Abstrakt: Background and Aims: The studies have shown that α-tocopherol supplementation could improve lipid profile in diabetes mellitus (DM) patients. Nonetheless, the result remains inconsistent. Therefore, this meta-analysis was performed to evaluate the efficacy of α-tocopherol supplement on lipid parameters in DM patients.
Methods: We conducted an extensive search via Cochrane Library, PubMed, Scopus, and Web of Science databases to acquire the reported RCTs up to October 2020.
Results: The results showed no effects of α-tocopherol supplementation on lipid profile in DM patients except when used ≥12 weeks.
Conclusions: α-tocopherol supplementation in DM patients had no significant effect on lipid profiles.
Competing Interests: Declaration of competing interest No conflict of interest declared by the authors.
(Copyright © 2021 Diabetes India. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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