Enhanced hippocampal theta rhythmicity and emergence of eta oscillation in virtual reality.

Autor: Safaryan K; Department of Physics and Astronomy, University of California, Los Angeles, Los Angeles, CA, USA. safaryan@ucla.edu., Mehta MR; Department of Physics and Astronomy, University of California, Los Angeles, Los Angeles, CA, USA. mayankmehta@ucla.edu.; W. M. Keck Center for Neurophysics, Integrative Center for Learning and Memory, and Brain Research Institute, University of California, Los Angeles, Los Angeles, CA, USA. mayankmehta@ucla.edu.; Department of Electrical and Computer Engineering, University of California, Los Angeles, Los Angeles, CA, USA. mayankmehta@ucla.edu.; Departments of Neurology and Neurobiology, University of California, Los Angeles, Los Angeles, CA, USA. mayankmehta@ucla.edu.
Jazyk: angličtina
Zdroj: Nature neuroscience [Nat Neurosci] 2021 Aug; Vol. 24 (8), pp. 1065-1070. Date of Electronic Publication: 2021 Jun 28.
DOI: 10.1038/s41593-021-00871-z
Abstrakt: Hippocampal theta rhythm is a therapeutic target because of its vital role in neuroplasticity, learning and memory. Curiously, theta differs across species. Here we show that theta rhythmicity is greatly amplified when rats run in virtual reality. A novel eta rhythm emerged in the CA1 cell layer, primarily in interneurons. Thus, multisensory experience governs hippocampal rhythms. Virtual reality can be used to boost or control brain rhythms and to alter neural dynamics, wiring and plasticity.
(© 2021. The Author(s), under exclusive licence to Springer Nature America, Inc.)
Databáze: MEDLINE
Externí odkaz: