[Paramecium, a model organism to study ciliogenesis and ciliopathies].

Autor:	Bouhouche K; Université Paris-Saclay, CEA, CNRS, Institut de biologie intégrative de la cellule (I2BC), 1 avenue de la Terrasse, 91198 Gif-sur-Yvette, France., Le Borgne P; Université Paris-Saclay, CEA, CNRS, Institut de biologie intégrative de la cellule (I2BC), 1 avenue de la Terrasse, 91198 Gif-sur-Yvette, France., Lemullois M; Université Paris-Saclay, CEA, CNRS, Institut de biologie intégrative de la cellule (I2BC), 1 avenue de la Terrasse, 91198 Gif-sur-Yvette, France., Tassin AM; Université Paris-Saclay, CEA, CNRS, Institut de biologie intégrative de la cellule (I2BC), 1 avenue de la Terrasse, 91198 Gif-sur-Yvette, France.
Jazyk:	francouzština
Zdroj:	Medecine sciences : M/S [Med Sci (Paris)] 2021 Jun-Jul; Vol. 37 (6-7), pp. 632-638. Date of Electronic Publication: 2021 Jun 28.
DOI:	10.1051/medsci/2021087
Abstrakt:	The cilium is a cell extension forming a distinct compartment of eukaryotic cell body with a complex and dynamic structure. This structure is highly conserved across species and ensures various functions as sensory and motility. In humans, ciliary dysfunction results in diseases (ciliopathies) that can affect all organs. Thanks to its complex ciliary structure, the unicellular and ciliated microorganism, Paramecium, constitutes a model of choice not only to study the structure, assembly and function of cilia but also to validate the specific role of mutations of genes linked to the ciliopathies. (© 2021 médecine/sciences – Inserm.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu