SARS-CoV-2-Induced Multisystem Inflammatory Syndrome in a Young Adult: Case Report.

Autor: Bulut H; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Internal Medicine, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands., Herbers AHE; Department of Internal Medicine, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands., Hageman IMG; Department of Internal Medicine, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands., Netten PM; Department of Internal Medicine, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands., de Jonge HJM; Department of Gastroenterology and Hepatology, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands., Joustra R; Department of Cardiology, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands., van de Veerdonk FL; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands., de Jager CPC; Department of Intensive Care Medicine, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands.
Jazyk: angličtina
Zdroj: SN comprehensive clinical medicine [SN Compr Clin Med] 2021; Vol. 3 (8), pp. 1773-1779. Date of Electronic Publication: 2021 Jun 20.
DOI: 10.1007/s42399-021-00998-x
Abstrakt: We describe a case of a previous healthy 20-year-old male athlete who presented with an atypical clinical profile with multiorgan involvement within five weeks after confirmed SARS-CoV-2 infection, suggestive for multisystem inflammatory syndrome (MIS); MIS is a rare, potentially life-threatening complication associated with SARS-CoV-2. MIS shares similar clinical features compatible with several overlapping lifethreatening hyperinflammatory syndromes, such as incomplete Kawasaki Disease (KD) and toxic shock syndrome (TSS) associated to a cytokine storm suggestive of a macrophage activation syndrome (MAS) without fulfilling the criteria for hemophagocytic lymphohistiocytosis (HLH), that may create a great challenge to distinguish between them. MIS should promptly be considered and treated, as uncontrolled MIS has a high mortality. In MIS cardiac involvement, heart failure may present as an additional problem, especially because volume loading is advised in accordance with proposed therapy. Carefully monitoring of the respiratory and cardiac status in response of resuscitation is therefore warranted.
Competing Interests: Conflict of InterestThe authors declare no competing interests.
(© The Author(s) 2021.)
Databáze: MEDLINE
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