Microbiological Findings of Symptomatic Vulvovaginitis in Chinese Prepubertal Girls.

Autor: Hu BF; Division of Infectious Diseases, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, People's Republic of China., Hua CZ; Division of Infectious Diseases, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, People's Republic of China. Electronic address: huachunzhen@zju.edu.cn., Sun LY; Department of Children's Gynecology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, People's Republic of China., Chao-Fang; Department of Clinical Laboratory Center, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, People's Republic of China., Zhou MM; Department of Clinical Laboratory Center, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, People's Republic of China.
Jazyk: angličtina
Zdroj: Journal of pediatric and adolescent gynecology [J Pediatr Adolesc Gynecol] 2021 Dec; Vol. 34 (6), pp. 799-804. Date of Electronic Publication: 2021 Jun 21.
DOI: 10.1016/j.jpag.2021.05.012
Abstrakt: Study Objective: To study the bacteria and fungi causing vulvovaginitis in prepubertal girls.
Design: Swabs from vaginal introitus were collected from patients with vulvovaginitis in 2018, and cultured for the identification of microorganisms with standard microbiological techniques.
Setting: A children's hospital in Hangzhou, East China.
Participants: A total of 1235 Chinese prepubertal girls diagnosed with vulvovaginitis.
Main Outcome Measure: Bacteria or fungi in pure cultures or as the predominant organism were defined as pathogens.
Results: A total of 1235 cases were diagnosed as vulvovaginitis, and 515 isolates were identified from 494 patients (40%, 494/1235). The most common pathogen was Streptococcus pyogenes (27.6%,142/515), followed by Haemophilus influenzae (27.2%,140/515), Candida albicans (22.3%,115/515), Staphylococcus aureus (5.8%, 30/515) and Escherichia coli (4.7%,24/515). All S pyogenes isolates were sensitive to penicillin, whereas 53.7% (73/136) of H influenzae isolates were sensitive to ampicillin, and 70.4% (19/27) of S aureus isolates were sensitive to oxacillin.
Conclusion: S pyogenes and H influenzae were the 2 most commonly identified pathogenic bacteria found in prepubertal girls with vulvovaginitis. Vulvovaginitis in prepubertal girls caused by C albicans may be more common in older children.
(Copyright © 2021 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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