BLAST from the Past: Impacts of Evolving Approaches on Studies of Evolution by Gene Duplication.

Autor: Chain FJJ; Department of Biological Sciences, University of Massachusetts Lowell, Massachusetts, USA., Assis R; Department of Electrical Engineering and Computer Science, Florida Atlantic University, Boca Raton, Florida, USA.; Institute for Human Health and Disease Intervention, Florida Atlantic University, Boca Raton, Florida, USA.
Jazyk: angličtina
Zdroj: Genome biology and evolution [Genome Biol Evol] 2021 Jul 06; Vol. 13 (7).
DOI: 10.1093/gbe/evab149
Abstrakt: In 1970, Susumu Ohno hypothesized that gene duplication was a major reservoir of adaptive innovation. However, it was not until over two decades later that DNA sequencing studies uncovered the ubiquity of gene duplication across all domains of life, highlighting its global importance in the evolution of phenotypic complexity and species diversification. Today, it seems that there are no limits to the study of evolution by gene duplication, as it has rapidly coevolved with numerous experimental and computational advances in genomics. In this perspective, we examine word stem usage in PubMed abstracts to infer how evolving discoveries and technologies have shaped the landscape of studying evolution by gene duplication, leading to a more refined understanding of its role in the emergence of novel phenotypes.
(© The Author(s) 2021. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.)
Databáze: MEDLINE