Yield of surgery in solid pseudopapillary neoplasms of the pancreas: A case series and literature review.

Autor:	Silano F; Digestive Surgery, Hospital São Rafael/Rede D'Or, Salvador 40285000, Bahia, Brazil. sdesilano@gmail.com., de Melo Amaral RB; Department of Surgery of the Upper Digestive System, São Rafael Hospital/Rede D'Or Hospital Group, Salvador 41253-190, Bahia, Brazil., Santana RC; Department of Surgery of the Upper Digestive System, São Rafael Hospital/Rede D'Or Hospital Group, Salvador 41253-190, Bahia, Brazil., Neves VC; Department of Surgery of the Upper Digestive System, São Rafael Hospital/Rede D'Or Hospital Group, Salvador 41253-190, Bahia, Brazil., Ardengh JC; Surgery and Anatomy, Hospital das Clinicas da Faculdade de Medicina de Ribeirão Preto - Universidade de São Paulo, São Paulo 04611-000, São Paulo, Brazil., do Amaral PCG; Department of Surgery of the Upper Digestive System, São Rafael Hospital/Rede D'Or Hospital Group, Salvador 41253-190, Bahia, Brazil.
Jazyk:	angličtina
Zdroj:	World journal of gastrointestinal oncology [World J Gastrointest Oncol] 2021 Jun 15; Vol. 13 (6), pp. 589-599.
DOI:	10.4251/wjgo.v13.i6.589
Abstrakt:	Background: Solid pseudopapillary neoplasms (SPN) of the pancreas represents approximately 2% of non-endocrine tumors of the pancreas. It is described in the literature as a rare and predominant tumor in young women. Aim: To report a case series with SPN and analyzing clinical, surgical, anatomopathological characteristics, as well as the prognosis and review of literature. Methods: Retrospective analysis of patients undergoing surgery, with histological diagnosis of SPN between 1998 and 2018, using standardized and prospectively completed forms, performed at the Surgery Service of the Upper Digestive System at Hospital São Rafael/Rede D'Or in Salvador - BA. Review of literature through a database search in MEDLINE/PubMed of retrospective articles. Results: Fourteen female patients with the average age of 31.6 years (range min-max) were selected. Twelve patients (85.7%) were asymptomatic, being an incidental diagnosis or due to screening for other reasons. One patient had abdominal pain due to gastric compression and another patient had jaundice. The 14 patients were staged with computerized tomography or magnetic resonance imaging. None had evidence of metastasis. In 8 patients (57.1%), the tumor was in the tail and body. The average size was 6.7 cm (range min-18). The type of surgery was according to the anatomical location of the tumor. There was no lymph node involvement. In two cases, vascular resection with the use of a prosthesis was required for reconstruction. The surgical margins were free. In all cases, postoperative immunohistochemistry confirmed that it was a solid pseudo-papillary neoplasia of the pancreas. There has been no disease recurrence in any case so far. Conclusion: The tumors had a benign, indolent and histopathological behavior compatible with the literature. Curative surgery is recommended in all cases. Competing Interests: Conflict-of-interest statement: None of the Authors has any conflict of interest related to the manuscript. (©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.)
Databáze:	MEDLINE
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