What is the impact of multimorbidity on the risk of hospitalisation in older adults? A systematic review study protocol.

Autor:	Rodrigues LP; Postgraduate Program in Health Sciences, Universidade Federal de Goiás, Goiânia, Goiás, Brazil., Rezende ATO; Postgraduate Program in Health Sciences, Universidade Federal de Goiás, Goiânia, Goiás, Brazil., Moura LANE; Postgraduate Program in Health Sciences, Universidade Federal de Goiás, Goiânia, Goiás, Brazil., Nunes BP; Department of Nursing in Collective Health and the Postgraduate Program in Nursing, Federal University of Pelotas, Pelotas, Brazil., Noll M; Instituto Federal Goiano, Ceres, Goiás, Brazil., de Oliveira C; Department of Epidemiology and Public Health, University College London, London, UK., Silveira EA; Postgraduate Program in Health Sciences, Universidade Federal de Goiás, Goiânia, Goiás, Brazil erikasil@terra.com.br.; Affiliate Academic, Department of Epidemiology and Public Health, University College London, London, UK.
Jazyk:	angličtina
Zdroj:	BMJ open [BMJ Open] 2021 Jun 23; Vol. 11 (6), pp. e049974. Date of Electronic Publication: 2021 Jun 23.
DOI:	10.1136/bmjopen-2021-049974
Abstrakt:	Introduction: The development of multiple coexisting chronic diseases (multimorbidity) is increasing globally, along with the percentage of older adults affected by it. Multimorbidity is associated with the concomitant use of multiple medications, a greater possibility of adverse effects, and increased risk of hospitalisation. Therefore, this systematic review study protocol aims to analyse the impact of multimorbidity on the occurrence of hospitalisation in older adults and assess whether this impact changes according to factors such as sex, age, institutionalisation and socioeconomic status. This study will also review the average length of hospital stay and the occurrence of hospital readmission. Methods and Analysis: A systematic review of the literature will be carried out using the PubMed, Embase and Scopus databases. The inclusion criteria will incorporate cross-sectional, cohort and case-control studies that analysed the association between multimorbidity (defined as the presence of ≥2 and/or ≥3 chronic conditions and complex multimorbidity) and hospitalisation (yes/no, days of hospitalisation and number of readmissions) in older adults (aged ≥60 years or >65 years). Effect measures will be quantified, including ORs, prevalence ratios, HRs and relative risk, along with their associated 95% CI. The overall aim of this study is to widen knowledge and to raise reflections about the association between multimorbidity and hospitalisation in older adults. Ultimately, its findings may contribute to improvements in public health policies resulting in cost reductions across healthcare systems. Ethics and Dissemination: Ethical approval is not required. The results will be disseminated via submission for publication to a peer-reviewed journal when complete. Prospero Registration Number: CRD42021229328. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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