Evaluation of children with type 1 diabetes mellitus in terms of overweight/obesity in tertiary care hospital.

Autor:	Bitkin EC; Department of Pediatrics, Van Yüzüncü Yıl University, Faculty of Medicine, Division of Pediatric Endocrinology, Van, Turkey., Kara C; Department of Pediatrics, Istinye University, Faculty of Medicine, Division of Pediatric Endocrinology, Istanbul, Turkey., Yılmaz GC; Department of Pediatrics, Muğla Sıtkı Koçman University, Faculty of Medicine, Division of Pediatric Endocrinology, Muğla, Turkey., Mammadova J; Department of Pediatrics, Istinye University, Faculty of Medicine, Division of Pediatric Endocrinology, Istanbul, Turkey., Aydın HM; Department of Pediatrics, Ondokuz Mayis University, Faculty of Medicine, Division of Pediatric Endocrinology, Samsun, Turkey.
Jazyk:	angličtina
Zdroj:	Journal of pediatric endocrinology & metabolism : JPEM [J Pediatr Endocrinol Metab] 2021 Jun 23; Vol. 34 (8), pp. 995-1000. Date of Electronic Publication: 2021 Jun 23 (Print Publication: 2021).
DOI:	10.1515/jpem-2021-0268
Abstrakt:	Objectives: Obesity is a growing problem in type 1 diabetes mellitus (T1DM) today. The aim of our study is to determine the frequency of overweight/obesity at the time of diagnosis and during follow-up in children with T1DM as well as review the conditions that may accompany. Methods: A total of 315 patients with T1DM were retrospectively analyzed. The patients were divided into two groups as normal weight and overweight/obese. The two groups were compared in terms of age at diagnosis, birth weight, anthropometric measurements, insulin dose used and blood pressure measurements, and insulin, c-peptide, hemoglobin A1c, triglyceride, and high-density lipoprotein levels at the time of diagnosis and follow-up. Results: The height, weight and body mass index standard deviation (BMI SD) scores, and c-peptide levels at the time of diagnosis of the overweight/obese group were higher than those with normal weight (p<0.001 and p = 0.008, respectively). The frequency of dyslipidemia and hypertension was higher in the overweight/obese group than in the normal weight group [18.2 vs. 5% (p = 0.015) and 10 vs. 1.5% (p = 0.003), respectively]. Conclusions: In our study, the fact that the overweight/obese group had higher BMI and c-peptide and lower HDL values at the time of diagnosis can be evaluated as indicators that insulin resistance syndrome can accompany T1DM from the beginning (double diabetes). When determining the treatment and follow-up strategies of patients with T1DM, considering the risk of obesity and taking the necessary precautions is very important in terms of morbidity. (© 2021 Walter de Gruyter GmbH, Berlin/Boston.)
Databáze:	MEDLINE
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