Suspected vertical transmission of Chagas disease caused by DTU TcIV in an infection probably transmitted orally, during anoutbreak in the Brazilian Amazon.

Autor:	Freitas VLT; Universidade de São Paulo, Faculdade de Medicina, São Paulo, São Paulo, Brazil., Esper HR; Universidade de São Paulo, Faculdade de Medicina, São Paulo, São Paulo, Brazil.; Hospital Municipal de Santarém, Núcleo de Medicina Tropical, Santarém, Pará, Brazil., Nakanishi ES; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, São Paulo, São Paulo, Brazil., Piotto MR; Universidade de São Paulo, Faculdade de Medicina, São Paulo, São Paulo, Brazil., Assy JGPL; Hospital Municipal de Santarém, Núcleo de Medicina Tropical, Santarém, Pará, Brazil., Berreta OCP; Hospital Municipal de Santarém, Núcleo de Medicina Tropical, Santarém, Pará, Brazil., Said RDC; Hospital Municipal de Santarém, Núcleo de Medicina Tropical, Santarém, Pará, Brazil., Segurado AAC; Universidade de São Paulo, Faculdade de Medicina, São Paulo, São Paulo, Brazil.; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, São Paulo, São Paulo, Brazil., Carvalho NB; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, São Paulo, São Paulo, Brazil., França FOS; Universidade de São Paulo, Faculdade de Medicina, São Paulo, São Paulo, Brazil.; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, São Paulo, São Paulo, Brazil., Lopes MH; Universidade de São Paulo, Faculdade de Medicina, São Paulo, São Paulo, Brazil.; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, São Paulo, São Paulo, Brazil.
Jazyk:	angličtina
Zdroj:	Revista do Instituto de Medicina Tropical de Sao Paulo [Rev Inst Med Trop Sao Paulo] 2021 Jun 18; Vol. 63, pp. e48. Date of Electronic Publication: 2021 Jun 18 (Print Publication: 2021).
DOI:	10.1590/S1678-9946202163048
Abstrakt:	This study describes difficulties in the monitoring of a child born during an oral outbreak of Chagas disease, in which there are several indications that the transmission occurred through the congenital route: 1. the mother was in the third trimester of pregnancy when she was infected; 2. She presented high parasitemia at the time of delivery; 3. In both, the mother and her daughter, T. cruzi was classified as DTU TcIV. The parasites were not found in the blood at birth and the infection was detected only three months later in an asymptomatic infant. As the mother and her child live in a highly endemic area, vector transmission could not be excluded during this period.
Databáze:	MEDLINE
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