Inoperable CASTLE of the thyroid gland treated with radical radiotherapy with complete remission.

Autor: Kovářová P; Department of Oncology and Radiotherapy, Charles University in Prague, Faculty of Medicine and University Hospital in Pilsen, alej Svobody 80, 304 60, Pilsen, Czech Republic., Vojtíšek R; Department of Oncology and Radiotherapy, Charles University in Prague, Faculty of Medicine and University Hospital in Pilsen, alej Svobody 80, 304 60, Pilsen, Czech Republic. vojtisekr@fnplzen.cz., Krčma M; Department of Internal Medicine, Charles University in Prague, Faculty of Medicine and University Hospital in Pilsen, alej Svobody 80, 304 60, Pilsen, Czech Republic., Daum O; Sikl's Department of Pathology, , Charles University in Prague, Faculty of Medicine and University Hospital in Pilsen, Edvarda Beneše 13, 305 99, Pilsen, Czech Republic.; Bioptical Laboratory, Mikulášské nám. 4, 326 00, Pilsen, Czech Republic., Baxa J; Department of Imaging Methods, Charles University in Prague, Faculty of Medicine and University Hospital in Pilsen, alej Svobody 80, 304 60, Pilsen, Czech Republic., Sukovská E; Department of Oncology and Radiotherapy, Charles University in Prague, Faculty of Medicine and University Hospital in Pilsen, alej Svobody 80, 304 60, Pilsen, Czech Republic., Fínek J; Department of Oncology and Radiotherapy, Charles University in Prague, Faculty of Medicine and University Hospital in Pilsen, alej Svobody 80, 304 60, Pilsen, Czech Republic.
Jazyk: angličtina
Zdroj: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] [Strahlenther Onkol] 2021 Sep; Vol. 197 (9), pp. 847-853. Date of Electronic Publication: 2021 Jun 23.
DOI: 10.1007/s00066-021-01800-6
Abstrakt: Carcinoma showing thymus-like elements (CASTLE) is an extremely rare malignant tumor of the thyroid gland and soft tissues of the neck with favorable prognosis. Histological features of the CASTLE are similar to thymic carcinoma, and it is assumed that it arises from the ectopic thymic tissue or the remnants of branchial pouches. The optimal treatment strategy is still uncertain because of the rarity of the tumor. The mainstay of treatment is surgery. The role of other modalities is unclear. We present a case report of a patient with locally advanced CASTLE of the thyroid gland who was not suitable for surgery and underwent radical radiotherapy with subsequent achievement of complete remission. We also present a literature review.
(© 2021. Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
Externí odkaz: