Caloric Restriction and Cardiovascular Health: the Good, the Bad, and the Renin-Angiotensin System.
| Autor: | de Souza AMA; Division of Nephrology and Hypertension, Department of Medicine, Georgetown University, Washington, District of Columbia., Ecelbarger CM; Division of Nephrology and Hypertension, Department of Medicine, Georgetown University, Washington, District of Columbia., Sandberg K; Division of Nephrology and Hypertension, Department of Medicine, Georgetown University, Washington, District of Columbia. |
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| Jazyk: | angličtina |
| Zdroj: | Physiology (Bethesda, Md.) [Physiology (Bethesda)] 2021 Jul 01; Vol. 36 (4), pp. 220-234. |
| DOI: | 10.1152/physiol.00002.2021 |
| Abstrakt: | Much excitement exists over the cardioprotective and life-extending effects of caloric restriction (CR). This review integrates population studies with experimental animal research to address the positive and negative impact of mild and severe CR on cardiovascular physiology and pathophysiology, with a particular focus on the renin-angiotensin system (RAS). We also highlight the gaps in knowledge and areas ripe for future physiological research. |
| Databáze: | MEDLINE |
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