DIGITAL BREAST TOMOSYNTHESIS AND FULL-FIELD DIGITAL MAMMOGRAPHY IN BREAST CANCER DETECTION ASSOCIATED WITH FOUR ASYMMETRY TYPES.

Autor:	Gurando AV; SI, ''INSTITUTE OF NUCLEAR MEDICINE AND DIAGNOSTIC RADIOLOGY OF NATIONAL ACADEMY OF MEDICAL SCIENCE OF UKRAINE'', KYIV, UKRAINE; MEDICAL CENTER, «VERUM EXPERT», KYIV, UKRAINE., Babkina TM; P.L. SHUPYK NATIONAL MEDICAL ACADEMY OF POSTGRADUATE EDUCATION, KYIV, UKRAINE., Dykan IM; SI, ''INSTITUTE OF NUCLEAR MEDICINE AND DIAGNOSTIC RADIOLOGY OF NATIONAL ACADEMY OF MEDICAL SCIENCE OF UKRAINE'', KYIV, UKRAINE., Kozarenko TM; P.L. SHUPYK NATIONAL MEDICAL ACADEMY OF POSTGRADUATE EDUCATION, KYIV, UKRAINE., Gurando VR; UZHHOROD NATIONAL UNIVERSITY, UZHHOROD, UKRAINE., Telniy VV; MEDICAL CENTER, «VERUM EXPERT», KYIV, UKRAINE.
Jazyk:	angličtina
Zdroj:	Wiadomosci lekarskie (Warsaw, Poland : 1960) [Wiad Lek] 2021; Vol. 74 (4), pp. 842-848.
Abstrakt:	Objective: The aim: Comparing sensitivity and specificity of digital breast tomosynthesis and full-field digital mammography in breast cancer detection associated with four different types of asymmetries according to BI-RADS Atlas. Patients and Methods: Materials and methods: Study included 201 patients with four types of asymmetries according BI-RADS atlas (asymmetry - 81 (40,3%), focal asymmetry - 82 (40,8%), global asymmetry - 36 (17,9%) and developing asymmetry - 2 (1,0%)) who underwent full-field digital mammography, digital breast tomosynthesis and hand-held full breast ultrasound from January 2017 to June 2018. The general rate of breast cancer for the 201 patients with asymmetries was 8 cases (4,0%) (IBC, n=6 (3,0%); DCIS, n=2 (1,0%) other findings associated with asymmetries were non-malignant, n=10 (5,0%) (sclerosing adenosis, n=5 (2,5%); fibroadenomatosis, n=3 (1,5%); simple cyst, n=1 (0,5%); radial scar associated with papilloma, typical ductal hyperplasia and sclerosing adenosis, n=1 (0,5%). Results: Results: Analysis of the results showed that sensitivity of digital breast tomosynthesis was 75.0% [95% CI, 34.91% to 96.81%] and specificity was 94.8% [95% CI, 90.68% to 97.49%] which was superior to full-field digital mammography sensitivity 50.0% [95% CI, 15.70% to 84.30%] and specificity 91.19% [95% CI, 86.27% to 94.78%] for breast cancer detection associated with different types of asymmetries. Conclusion: Conclusions: Using of digital breast tomosynthesis in assessment of breast asymmetries can improve sensitivity and specificity in breast cancer detection and reduce number of unnecessary biopsies and short-interval follow-up examinations.
Databáze:	MEDLINE
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