Contact Dermatitis Associated With Hair Care Products: A Retrospective Analysis of the North American Contact Dermatitis Group Data, 2001-2016.

Autor:	Warshaw EM, Ruggiero JL, DeKoven JG; Division of Dermatology, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada., Maibach HI; Department of Dermatology, University of California San Francisco., Atwater AR; Department of Dermatology, Duke University Medical Center, Durham, NC., Taylor JS; Department of Dermatology, Cleveland Clinic, OH., Zug KA; Department of Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, NH., Reeder MJ; Department of Dermatology, University of Wisconsin School of Medicine and Public Health, Madison, WI., Silverberg JI; Department of Dermatology, The George Washington University School of Medicine and Health Sciences, Washington, DC., Sasseville D; Division of Dermatology, Montreal General Hospital, McGill University, Quebec, Canada., Fowler JF Jr; Division of Dermatology, University of Louisville, KY., Fransway AF; Associates in Dermatology, Fort Myers, FL., Pratt MD; Division of Dermatology, University of Ottawa, Ontario, Canada., Belsito DV; Department of Dermatology, Columbia University Irving Medical School, New York, NY., DeLeo VA; Department of Dermatology, Keck School of Medicine, Los Angeles, CA.
Jazyk:	angličtina
Zdroj:	Dermatitis : contact, atopic, occupational, drug [Dermatitis] 2022 Jan-Feb 01; Vol. 33 (1), pp. 91-102.
DOI:	10.1097/DER.0000000000000760
Abstrakt:	Background: Hair care products (HCPs) may cause both allergic contact dermatitis (ACD) and irritant contact dermatitis (ICD). Objectives: The aims of the study were to determine the prevalence of HCP-associated ICD/ACD and to characterize relevant allergens. Methods: This study is a retrospective analysis of North American Contact Dermatitis Group (NACDG) patch test data, 2001-2016. Results: Of 38,775 patients tested, 3481 (9.0%) had positive patch test reactions associated with HCPs. The HCP-positive patients were significantly more likely to be female (79.9% vs 66.0%) and/or have primary sites of dermatitis on the face (32.0% vs 27.8%) or scalp (15.4% vs 2.2%) compared with the HCP-negative patients (P < 0.0001). Of 4908 HCP-associated positive patch test reactions, 86.9% (n = 4263) were due to allergens on the NACDG screening series; p-phenylenediamine (35.8%), methylisothiazolinone (9.7%), methylchloroisothiazolinone/methylisothiazolinone (8.7%), and cocamidopropyl betaine (5.9%) were the most frequent. Most reactions (87.7%, 3736/4263) were currently clinically relevant. The most common job associated with 366 occupationally related NACDG HCP-associated allergens was hairdresser/cosmetologist (71.9%). Two hundred eighty-two patients (0.7%) had ICD associated with HCPs. Shampoo/conditioners were the most frequent source of NACDG HCP-associated reactions (47.3%) and HCP-associated ICD (45.0%). Conclusions: Of the HCP-positive patients, 18.5% had HCP reactions to allergens not on the NACDG screening series, underscoring the importance of patch testing to expanded series in patients suspected of HCP allergy. Competing Interests: A.R.A. received a Pfizer Independent Grant for Learning & Change and has consulted for Henkel. E.M.W. has received research funding from WEN by Chaz Dean. She has also served as a consultant for Noven Pharmaceuticals, Inc, and WEN by Chaz Dean. J.S.T. owns shares of stock in AstraZeneca, Cigna, Merck, Johnson & Johnson, and OPKO Health. He has consulted for Kao Brands and Monsanto (Bayer), is a member of the Cosmetic Ingredient Review Steering Committee, and has a nondependent child employed by Pfizer. Sasseville receives royalties from UpToDate (Wolters Kluwer Health). The other authors have no funding or conflicts of interest to declare. (Copyright © 2021 American Contact Dermatitis Society. All Rights Reserved.)
Databáze:	MEDLINE
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