Transition-Metal Catalyzed Stereoselective Desymmetrization of Prochiral Cyclohexadienones.

Autor: Munakala A; Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad, 500007, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India., Phanindrudu M; Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad, 500007, India., Chegondi R; Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad, 500007, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Jazyk: angličtina
Zdroj: Chemical record (New York, N.Y.) [Chem Rec] 2021 Dec; Vol. 21 (12), pp. 3689-3726. Date of Electronic Publication: 2021 Jun 19.
DOI: 10.1002/tcr.202100136
Abstrakt: The development of transition-metal catalyzed enantioselective and diastereoselective transformations has contributed many advances in the field of synthetic organic chemistry. Particularly, stereoselective desymmetrization of prochiral cyclohexadienones represents a powerful strategy for accessing highly functionalized and stereochemically enriched scaffolds, which are often found in biologically active compounds and natural products. In recent years, several research groups including our group have made a significant progress on transition-metal catalyzed stereoselective desymmetrizations of 2,5-cyclohexadienones. In this account, we will provide an overview of the recent developments in this area employing Pd, Cu, Rh, Au, Ag, Ni, Co, and Mn-catalysts.
(© 2021 The Chemical Society of Japan & Wiley-VCH GmbH.)
Databáze: MEDLINE
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