Impact of COVID-19 pandemic on asthma symptoms and management: A prospective analysis of asthmatic children in Ecuador.

Autor:	Ochoa-Avilés AM; Department of Biosciences, Faculty of Chemistry, University of Cuenca, Cuenca, Azuay, Ecuador., Ochoa-Avilés C; Department of Biosciences, Faculty of Chemistry, University of Cuenca, Cuenca, Azuay, Ecuador.; Instituto de Ciencias da Saude, Universidade Federal da Bahia, Salvador, Bahía, Brazil., Morillo-Argudo DA; School of Medicine, International University of Ecuador, Quito, Pichincha, Ecuador., Molina-Cando MJ; Department of Biosciences, Faculty of Chemistry, University of Cuenca, Cuenca, Azuay, Ecuador.; School of Medicine, International University of Ecuador, Quito, Pichincha, Ecuador., Rodas-Espinoza CR; Faculty of Medicine, University of Azuay, Cuenca, Azuay, Ecuador., Chis Ster I; Institute of Infection and Immunity, St George's University of London, London, UK., Maestre Calderón MP; Department of Pediatrics Hospital Vicente Corral Moscoso, Cuenca, Azuay, Ecuador., Maldonado G A; Universidad San Francisco de Quito School of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hospital General Docente de Calderón, Quito, Pichincha, Ecuador., Arteaga Vaca K; Hospital Regional Verdi Cevallos, Portoviejo, Manabí, Ecuador., Rodriguez A; School of Medicine, International University of Ecuador, Quito, Pichincha, Ecuador., Cruz AA; Fundação ProAR and Universidade Federal da Bahia, Salvador, Brazil., Romero-Sandoval N; School of Medicine, International University of Ecuador, Quito, Pichincha, Ecuador., Cooper PJ; School of Medicine, International University of Ecuador, Quito, Pichincha, Ecuador.; Institute of Infection and Immunity, St George's University of London, London, UK.
Jazyk:	angličtina
Zdroj:	The World Allergy Organization journal [World Allergy Organ J] 2021 Jun 05; Vol. 14 (6), pp. 100551. Date of Electronic Publication: 2021 Jun 05 (Print Publication: 2021).
DOI:	10.1016/j.waojou.2021.100551
Abstrakt:	Background: Asthma affects up to 33% of children in Latin American settings. The ongoing COVID-19 pandemic has had a significant impact on access to and use of health services. We aimed to evaluate the impact of the COVID-19 lockdown on asthma exacerbations, medical facility visits, and use of asthma medications in children. Methods: We used data from a prospective cohort of 213 children aged 5-17 years in 3 Ecuadorian cities and analysed the impact of the COVID-19 lockdown on asthma. Outcomes (asthma exacerbations, emergency room [ER] visits, planned and unplanned outpatient visits, and use of inhaled corticosteroids and Beta-2 agonists) were analysed using repeated Poisson counts (ie, number of events per participant before and during the COVID-19 lockdown). Results: During compared to before lockdown: a) the number of asthma exacerbations remained constant (IRR, 0.87; 95% CI: 0.72-1.05; p = 0.152); b) outpatient visits (IRR 0.26, 95% CI 0.14-0.47, p < 0.001) declined 74% while ER visits declined 89% (IRR 0.11, 95% CI 0.04-0.32, p < 0.001); and c) there was no change in inhaled corticosteroids use (IRR 1.03, 95% CI 0.90-1.16, P = 0.699) while Beta-2 agonist use increased (IRR 1.32, 95% CI 1.10-1.58, P = 0.003). Conclusions: In a cohort of Ecuadorian children with asthma, health services attendance decreased dramatically after COVID-19 lockdown, but asthma exacerbations and use of inhaled corticosteroids were unchanged. Future analyses will address the question of the effect of SARS-CoV-2 infection on asthma exacerbations and control in this paediatric population. Competing Interests: The authors report no competing interests. (© 2021 The Author(s).)
Databáze:	MEDLINE
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