Consensus for the management of pancreatic exocrine insufficiency: UK practical guidelines.

Autor:	Phillips ME; Nutrition and Dietetics, Royal Surrey Hospital NHS Foundation Trust, Guildford, UK mary.phillips1@nhs.net., Hopper AD; Department of Gastroenterology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Leeds JS; HPB Unit, Freeman Hospital, Newcastle Upon Tyne, Tyne and Wear, UK., Roberts KJ; HPB Surgery, Queen Elizabeth Hospital Birmingham, Birmingham, UK., McGeeney L; Nutrition and Dietetics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Duggan SN; Department of Surgery, Trinity College Dublin, Dublin, Ireland., Kumar R; HPB Surgery, Royal Surrey Hospital NHS Foundation Trust, Guildford, UK.
Jazyk:	angličtina
Zdroj:	BMJ open gastroenterology [BMJ Open Gastroenterol] 2021 Jun; Vol. 8 (1).
DOI:	10.1136/bmjgast-2021-000643
Abstrakt:	Introduction: Pancreatic exocrine insufficiency is a finding in many conditions, predominantly affecting those with chronic pancreatitis, pancreatic cancer and acute necrotising pancreatitis. Patients with pancreatic exocrine insufficiency can experience gastrointestinal symptoms, maldigestion, malnutrition and adverse effects on quality of life and even survival.There is a need for readily accessible, pragmatic advice for healthcare professionals on the management of pancreatic exocrine insufficiency. Methods and Analysis: A review of the literature was conducted by a multidisciplinary panel of experts in pancreatology, and recommendations for clinical practice were produced and the strength of the evidence graded. Consensus voting by 48 pancreatic specialists from across the UK took place at the 2019 Annual Meeting of the Pancreatic Society of Great Britain and Ireland annual scientific meeting. Results: Recommendations for clinical practice in the diagnosis, initial management, patient education and long term follow up were developed. All recommendations achieved over 85% consensus and are included within these comprehensive guidelines. Competing Interests: Competing interests: MEP has received honoraria for teaching and resource development from Mylan, Nutricia, and Sanofi. AH has received honoraria for teaching and resource development from Mylan. JSL has received honoraria for teaching and consulting from Mylan. KJR has received honoraria for teaching from Mylan and Abbott. LM has received honoraria for teaching and conference attendance from Mylan. SND has received honoraria for teaching, consulting and conference attendance from Mylan and Abbott. RK has received honoraria for teaching from Mylan. (© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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