Autor: |
Guarino C; Unit of Bronchoscopy, Monaldi Hospital-A.O. Dei Colli of Naples, Napoli, Italy., Cesaro C; Unit of Bronchoscopy, Monaldi Hospital-A.O. Dei Colli of Naples, Napoli, Italy., La Cerra G; Unit of Bronchoscopy, Monaldi Hospital-A.O. Dei Colli of Naples, Napoli, Italy., Lucci R; Unit of Pathological Anatomy, Monaldi Hospital-A.O. Dei Colli of Naples, Napoli, Italy., Cesaro F; Unit of Emergency Medicine and Surgery and First Aid, C.T.O. Hospital, Napoli, Italy., Zamparelli E; Unit of Anesthesia and Resuscitation, Monaldi Hospital-A.O. Dei Colli of Naples, Napoli, Italy. |
Abstrakt: |
Malignant central airway obstruction is a life-threatening condition that often causes respiratory failure. In many cases, treatment of tumor in rigid bronchoscopy must be performed urgently, soothing respiratory symptoms and improving patient quality of life, in many cases reducing time to and allowing application of oncologic therapies. Immuno-oncologic therapies target the immune system selectively and are therefore much less toxic than standard chemotherapies, sometimes leading to outstanding results in advanced cancers for which there were no effective treatments until a few years ago. This report shows the effect of the joint application of rigid bronchoscopy and targeted immunotherapy in an emergency scenario, resulting in an unexpected extraordinary therapeutic success. |