A Leep1 into migration and macropinocytosis.

Autor: Koh YWH; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia., Stow JL; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia.
Jazyk: angličtina
Zdroj: The Journal of cell biology [J Cell Biol] 2021 Jul 05; Vol. 220 (7). Date of Electronic Publication: 2021 Jun 15.
DOI: 10.1083/jcb.202105141
Abstrakt: Actin organization underpins conserved functions at the leading edge of cells. In this issue, Yang et al. (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202010096) characterize Leep1 as a bi-functional regulator of migration and macropinocytosis through PIP3 and the Scar/WAVE complex.
(© 2021 Koh and Stow.)
Databáze: MEDLINE