A spectrofluorimetric method for the determination of pindolol in natural waters using various organic and cyclodextrin media.

Autor: Gueye C; Laboratoire Géomatériaux et Environnement (LGE), EA 4119, Université Paris-Est Marne-la-Vallé, 5 Boulevard Descartes, Bâtiment IFI, 77454, Marne-la-Vallée Cedex 2, France.; Laboratoire de Photochimie et d'Analyse, Département de Chimie, Faculté des Sciences et Techniques, Université Cheikh Anta Diop, Dakar, Senegal., Aaron JJ; Laboratoire Géomatériaux et Environnement (LGE), EA 4119, Université Paris-Est Marne-la-Vallé, 5 Boulevard Descartes, Bâtiment IFI, 77454, Marne-la-Vallée Cedex 2, France. jeanjacquesaaron@yahoo.fr., Gaye-Seye MD; Laboratoire Géomatériaux et Environnement (LGE), EA 4119, Université Paris-Est Marne-la-Vallé, 5 Boulevard Descartes, Bâtiment IFI, 77454, Marne-la-Vallée Cedex 2, France.; Laboratoire de Photochimie et d'Analyse, Département de Chimie, Faculté des Sciences et Techniques, Université Cheikh Anta Diop, Dakar, Senegal., Cisse L; Laboratoire de Photochimie et d'Analyse, Département de Chimie, Faculté des Sciences et Techniques, Université Cheikh Anta Diop, Dakar, Senegal., Oturan N; Laboratoire Géomatériaux et Environnement (LGE), EA 4119, Université Paris-Est Marne-la-Vallé, 5 Boulevard Descartes, Bâtiment IFI, 77454, Marne-la-Vallée Cedex 2, France., Oturan MA; Laboratoire Géomatériaux et Environnement (LGE), EA 4119, Université Paris-Est Marne-la-Vallé, 5 Boulevard Descartes, Bâtiment IFI, 77454, Marne-la-Vallée Cedex 2, France.
Jazyk: angličtina
Zdroj: Environmental science and pollution research international [Environ Sci Pollut Res Int] 2021 Oct; Vol. 28 (39), pp. 55029-55040. Date of Electronic Publication: 2021 Jun 14.
DOI: 10.1007/s11356-021-14801-w
Abstrakt: A simple, sensitive, and rapid spectrofluorimetric method was developed for the determination of the β-blocker pindolol. The native fluorescence of pindolol was measured in different organic solvents and in cyclodextrin aqueous media. The highest fluorescence signal was obtained in 2-propanol at λ em = 303 nm with λ ex = 260 nm. Analytical figures of merit for the spectrofluorimetric determination of pindolol were satisfactory, with wide linear dynamic range (LDR) values of two orders of magnitude, and rather low limit of detection (LOD) values between 0.2 and 8.7 ng/mL. Moreover, the addition of cyclodextrins (HP-β-CD and β-CD) in aqueous media enhanced the fluorescence of pindolol. In addition, the inclusion complexes of pindolol with cyclodextrins were investigated and the stability constants of complexes were calculated by means of the method of nonlinear regression (NLR). The method was successfully applied to the analysis of tap water and natural water samples, spiked with pindolol.
(© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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