Comparison of frailty associated factors between older adult patients with rheumatoid arthritis and community dwellers.

Autor: Ozeki S; Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan; Department of Frailty, Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Obu, Japan., Takeuchi K; Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan. Electronic address: k.takeuchi@med.nagoya-u.ac.jp., Yasuoka M; Department of Frailty, Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Obu, Japan; Department of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Kamiji K; Department of Frailty, Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Obu, Japan; Department of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Kojima T; Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan., Waguri-Nagaya Y; Department of Orthopedic Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan; Center of Joint Surgery for Rheumatic Diseases and Osteoporosis, Nagoya City East Medical Center, Nagoya, Japan., Ojima T; Department of Community Health and Preventive Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan., Kondo K; Department of Gerontological Evaluation, Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Obu, Japan; Department of Social Preventive Medical Sciences, Chiba University, Chiba, Japan., Wakai K; Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan., Kojima M; Department of Frailty, Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Obu, Japan; Department of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Jazyk: angličtina
Zdroj: Archives of gerontology and geriatrics [Arch Gerontol Geriatr] 2021 Sep-Oct; Vol. 96, pp. 104455. Date of Electronic Publication: 2021 Jun 02.
DOI: 10.1016/j.archger.2021.104455
Abstrakt: Purpose: To determine whether frailty associated factors differ between community dwellers and older adult patients with rheumatoid arthritis (RA).
Methods: We used the cross-sectional data for patients with RA from the RA epidemiological quality-of-life study (n = 210, mean age 71.8 ± 3.7 years) and community dwellers from the Japan Gerontological Evaluation Study (n = 53,255, mean age 71.7 ± 4.0 years). Frailty status was assessed using the Kihon Checklist (KCL), and the primary outcome was frailty (KCL score ≥8 points). Information on predictor variables, including age, sex, marital status, educational level, body mass index (BMI), drinking and smoking status and social participation were obtained from a standardized questionnaire. We employed Poisson regression to calculate the prevalence ratio (PR) of frailty according to its predictors.
Results: We found frailty in 37.6% of the patients with RA and 15.7% of the community dwellers. In the multivariate models, BMI and social participation were independently associated with frailty in patients with RA (BMI <18.5: PR, 1.62; 95% confidence interval [CI] 1.09-2.41. BMI ≥25.0: PR, 1.81; 95% CI 1.20-2.71. Active social participation: PR, 0.61; 95% CI 0.42-0.87) and community dwellers (BMI <18.5: PR, 1.77; 95% CI 1.67-1.88. BMI ≥25.0: PR, 1.27; 95% CI 1.22-1.33. Active social participation: PR, 0.46; 95% CI 0.44-0.48). All other predictors were significantly associated with frailty in the community dwellers.
Conclusion: Maintaining appropriate body weight and participating in social activities are important for preventing frailty in patients with RA as well as community dwellers.
(Copyright © 2021 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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