Incidence of endophthalmitis following intravitreal anti VEGF injections at a tertiary care hospital in Pakistan.

Autor: Shaheen F; Department of Ophthalmology, Shifa International Hospital, Islamabad, Pakistan., Awan MA; Department of Vitreoretinal Surgery, Shifa International Hospital, Islamabad, Pakistan., Hafeez A; Department of Ophthalmology, Shifa International Hospital, Islamabad, Pakistan., Haq A; Department of Ophthalmology, Shifa International Hospital, Islamabad, Pakistan., Malik RZ; Department of Ophthalmology, Shifa International Hospital, Islamabad, Pakistan.
Jazyk: angličtina
Zdroj: JPMA. The Journal of the Pakistan Medical Association [J Pak Med Assoc] 2021 Apr; Vol. 71 (4), pp. 1184-1188.
DOI: 10.47391/JPMA.212
Abstrakt: Objective: To assess the rate of infectious endophthalmitis with anti-vascular endothelial growth factor injection, and to evaluate institutional procedure protocol in this regard.
Methods: The retrospective consecutive case series was conducted at Shifa International Hospital, Islamabad, Pakistan, from August 2018 to January 2019, and comprised 5-year data from August 2014 to July 2019 related to patients who underwent intravitreal anti-vascular endothelial growth factor injections. Data was analysed using SPSS 21.
Results: Of the 7,542 injections administered to 2,734 patients, 5,976(79.2%) were bevacizumab, 1,081(14.3%) ranibizumab and 485(6.4%) aflibercept. There was 1(0.01%) case of infectious endophthalmitis which was treated with 25 gauge pars plana vitrectomy.
Conclusions: The institutional procedure protocol was found to be effective as the rate of infectious endophthalmitis was lower than what is reported in literature.
Databáze: MEDLINE