Methods Used to Identify, Test, and Assess Impact on Preferences of Bolt-Ons: A Systematic Review.

Autor: Geraerds AJLM; Erasmus MC, University Medical Center Rotterdam, Department of Public Health, The Netherlands. Electronic address: a.geraerds@erasmusmc.nl., Bonsel GJ; Erasmus MC, University Medical Center Rotterdam, Department of Public Health, The Netherlands; EuroQol Research Foundation, Rotterdam, The Netherlands., Janssen MF; Section Medical Psychology and Psychotherapy, Department of Psychiatry, Erasmus MC, Rotterdam, The Netherlands; EuroQol Research Foundation, Rotterdam, The Netherlands., Finch AP; EuroQol Research Foundation, Rotterdam, The Netherlands., Polinder S; Erasmus MC, University Medical Center Rotterdam, Department of Public Health, The Netherlands., Haagsma JA; Erasmus MC, University Medical Center Rotterdam, Department of Public Health, The Netherlands.
Jazyk: angličtina
Zdroj: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research [Value Health] 2021 Jun; Vol. 24 (6), pp. 901-916. Date of Electronic Publication: 2021 Mar 18.
DOI: 10.1016/j.jval.2020.12.011
Abstrakt: Objectives: The question of whether additional dimensions should be added to the EQ-5D, so-called bolt-ons, has been researched since the 1990s. Several candidate bolt-ons have been tested. The aim of this systematic review was to provide an overview of EQ-5D bolt-on studies, including the origin of possible suitable bolt-ons, their format, and methods that were used to examine their value.
Methods: Studies were identified through database search and reference screening and assessed based on a set of inclusion criteria. All studies that investigated bolt-ons for the EQ-5D were eligible for inclusion. Two reviewers independently extracted information from all included studies on objectives, study design, EQ-5D version used, the investigated bolt-ons, methods used to achieve objectives, and outcomes.
Results: Of 308 initially identified studies, 28 studies met the inclusion criteria. Of these studies, 3 identified potentially suitable bolt-on dimensions, 13 investigated the psychometric performance of EQ-5D + bolt-on(s), and 6 investigated the impact of the bolt-on on health state preferences. In total, 26 bolt-ons were identified, of which cognition was the most frequently mentioned. A wide variety of bolt-on identification methods, psychometric performance tests, and health state valuation methods were used in the included studies.
Conclusion: A range of bolt-on dimensions has been investigated using diverse methods. Guidelines are needed to standardize the wording of the bolt-on dimension and response options, evaluate minimal important gain of the bolt-on, and facilitate quality assessment of bolt-on studies. Subsequently, guidelines will facilitate decision making on whether or not to implement a bolt-on dimension to the EQ-5D.
(Copyright © 2021 ISPOR–The Professional Society for Health Economics and Outcomes Research. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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