Importation of Entamoeba histolytica and predominance of Klebsiella pneumoniae in liver abscesses: a 7-year retrospective cohort study from the United Arab Emirates.

Autor: Mousa H; Department of Surgery, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.; Surgical Institute, Al Ain Hospital, Al Ain, United Arab Emirates., Al-Bluwi GSM; Department of Internal Medicine, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates., Al Drini ZFM; Department of Internal Medicine, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates., Gasmelseed HI; Division of Infectious Diseases, Al Ain Hospital, Al Ain, United Arab Emirates., Alkoteesh JA; Clinical Imaging Institute, Al Ain Hospital, Al Ain, United Arab Emirates., Babiker ZOE; Department of Internal Medicine, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates. zahirbabiker@doctors.org.uk.; Division of Infectious Diseases, Al Ain Hospital, Al Ain, United Arab Emirates. zahirbabiker@doctors.org.uk.; Present Address: Division of Infectious Diseases, Sheikh Shakhbout Medical City in Partnership with Mayo Clinic, Abu Dhabi, United Arab Emirates. zahirbabiker@doctors.org.uk.
Jazyk: angličtina
Zdroj: Tropical diseases, travel medicine and vaccines [Trop Dis Travel Med Vaccines] 2021 Jun 12; Vol. 7 (1), pp. 17. Date of Electronic Publication: 2021 Jun 12.
DOI: 10.1186/s40794-021-00140-8
Abstrakt: Background: There is a dearth of information on liver abscesses in the United Arab Emirates. Herein, we describe the clinical features of liver abscesses and determine their incidence rates and clinical outcomes.
Methods: We retrospectively reviewed the clinical charts of adult patients with a primary diagnosis of liver abscess at a major hospital over a 7-year period.
Results: Amongst 45 patients, 82.2% (37/45) had a pyogenic liver abscess (PLA) and 17.8% (8/45) had amoebic liver abscesses (ALA). Overall, patients were young (median age 42 years, IQR 35-52), mostly males (77.8%, 35/45) from the Indian subcontinent (55.6%, 25/45), presented with fever (88.9%, 40/45) and abdominal pain (88.9%, 40/45), and had a solitary abscess on imaging (71.1% (32/45). Crude annual incidence rates were 35.9/100,000 hospital admissions (95% CI 26.2-48.0) and 5.9/100,000 inhabitants (95% CI 4.3-7.9). All ALA patients were from the Indian subcontinent (100%, 8/8). Klebsiella pneumoniae was the most frequent pathogen in PLA (43.2% [16/37], 95% CI 27.1-60.5%). The hospital stay was shorter in ALA (7.5 days, IQR 7-8.5) than in PLA (14 days, IQR 9-17). No deaths were recorded within 30 days of hospitalisation.
Conclusions: ALA was exclusively seen in migrants from the Indian subcontinent, suggesting importation. Further research to characterise K. pneumoniae isolates and assess potential risk factors is needed.
Databáze: MEDLINE
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