Symptomatic SARS-CoV-2 infections after full schedule BNT162b2 vaccination in seropositive healthcare workers: a case series from a single institution.

Autor: Baj A; Department of Medicine and Surgery, University of Insubria, Varese, Italy., Novazzi F; Laboratory of Microbiology, ASST dei Sette Laghi, Varese, Italy., Genoni A; Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy., Ferrante FD; Laboratory of Microbiology, ASST dei Sette Laghi, Varese, Italy., Taborelli S; Unit of Occupational Medicine, ASST dei Sette Laghi, Varese, Italy., Pini B; Clinical Pathology Unit, St. Anna Hospital, Como, Italy., Partenope M; Clinical Pathology Unit, St. Anna Hospital, Como, Italy., Valli M; Clinical Pathology Unit, St. Anna Hospital, Como, Italy., Gasperina DD; Department of Medicine and Surgery, University of Insubria, Varese, Italy., Capuano R; Laboratory of Microbiology, ASST dei Sette Laghi, Varese, Italy., Prestia M; Laboratory of Microbiology, ASST dei Sette Laghi, Varese, Italy., Spezia PG; Department of Translational Research, University of Pisa, Pisa, Italy., Azzi L; Unit of Oral Medicine and Pathology, ASST dei Sette Laghi, Varese, Italy., Focosi D; North-Western Tuscany Blood Bank, Pisa University Hospital, Pisa, Italy., Maggi F; Department of Medicine and Surgery, University of Insubria, Varese, Italy.; Laboratory of Microbiology, ASST dei Sette Laghi, Varese, Italy.
Jazyk: angličtina
Zdroj: Emerging microbes & infections [Emerg Microbes Infect] 2021 Dec; Vol. 10 (1), pp. 1254-1256.
DOI: 10.1080/22221751.2021.1942230
Abstrakt: We report 11 cases of SARS-CoV-2 infection in healthcare workers (HCW) naïve for COVID-19 and seropositive after the second dose of the BNT162b2 mRNA vaccine. Based on voluntary-based surveillance, they tested positive for different strains of SARS-CoV-2, as Spike gene sequencing showed. Five of them reported mild symptoms. Given the risk for SARS-CoV-2 introduction from asymptomatic vaccinees, this case series suggests the need to continue nasopharyngeal screening programmes.
Databáze: MEDLINE