Coronavirus Disease and Cardiovascular Disease: A Literature Review.

Autor:	Vudathaneni VKP; Physician, North Central Bronx Hospital, 3424 Kossuth Ave, Bronx., Nadella SB; Resident Physician, James J Peter VA Medical center, 130W Kingsbridge Road, Bronx 10468, New York., Lanke RB; Associate General Dentist, C/O Familia Dental LLC, 3200 Andrews Hwy, Ste 400, Midland Texas, United States., Boyapati R; Department of Periodontology, Sibar Institute of Dental Sciences, Guntur, Andhra Pradesh, India.
Jazyk:	angličtina
Zdroj:	Journal of clinical and translational research [J Clin Transl Res] 2021 Mar 24; Vol. 7 (2), pp. 156-162. Date of Electronic Publication: 2021 Mar 24 (Print Publication: 2021).
Abstrakt:	Background and Aim: Although severe acute respiratory syndrome coronavirus 2 primarily affects the respiratory system, involvement of cardiovascular system is not uncommon and a range of cardiac manifestations among Coronavirus Disease (COVID-19) patients were reported in the literature. Furthermore, it is evident from scientific literature that the incidence of deaths and hospitalizations has been increasingly more among COVID-19 subjects with pre-existing cardiovascular disease (CVD). Various pathophysiological mechanisms have been proposed to explain the cardiovascular involvement in COVID-19. Another emerging significant concern is the varying presentations of COVID-19 and side effects due to the medication used in the management of COVID-19 patients. This review attempts to provide a comprehensive overview of the existing literature on the possible association between CVD and COVID-19 with emphasis on the pathophysiological mechanisms, cardiac manifestations, and impact of medications used for COVID-19 on cardiovascular health. Based on the available literature, we conclude that though CVD could not be reckoned as an independent risk factor for COVID-19 infection, it is evident that pre-existing CVD has an influence on the severity of COVID-19 infection and associated mortality. Relevance for Patients: Literature suggests that people with pre-existing CVD are at increased risk for COVID-19 and associated severity. Consequently, it becomes important to thoroughly gain insights into the possible pathophysiological mechanisms, cardiac manifestations in COVID-19, and the impact of COVID-19 treatment on the cardiovascular system. Competing Interests: The authors declare no conflicts of interest. (Copyright: © Whioce Publishing Pte. Ltd.)
Databáze:	MEDLINE
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