Pathogens associated with acute diarrhea, and comorbidity with malaria among children under five years old in rural Burkina Faso.

Autor:	Lompo P; Institut de Recherche en Science de la Santé, Unité de Recherche Clinique de Nanoro, Ouagadougou, Burkina Faso., Tahita MC; Institut de Recherche en Science de la Santé, Unité de Recherche Clinique de Nanoro, Ouagadougou, Burkina Faso., Sorgho H; Institut de Recherche en Science de la Santé, Unité de Recherche Clinique de Nanoro, Ouagadougou, Burkina Faso., Kaboré W; Institut de Recherche en Science de la Santé, Unité de Recherche Clinique de Nanoro, Ouagadougou, Burkina Faso., Kazienga A; Institut de Recherche en Science de la Santé, Unité de Recherche Clinique de Nanoro, Ouagadougou, Burkina Faso., Nana ACB; Institut de Recherche en Science de la Santé, Unité de Recherche Clinique de Nanoro, Ouagadougou, Burkina Faso., Natama HM; Institut de Recherche en Science de la Santé, Unité de Recherche Clinique de Nanoro, Ouagadougou, Burkina Faso., Bonkoungou IJO; University of Ouagadougou I, Prof. Joseph Ki Zerbo, Ouagadougou, Burkina Faso.; Laboratoire National de Santé Publique, Ouagadougou, Burkina Faso., Barro N; University of Ouagadougou I, Prof. Joseph Ki Zerbo, Ouagadougou, Burkina Faso., Tinto H; Institut de Recherche en Science de la Santé, Unité de Recherche Clinique de Nanoro, Ouagadougou, Burkina Faso.
Jazyk:	angličtina
Zdroj:	The Pan African medical journal [Pan Afr Med J] 2021 Mar 12; Vol. 38, pp. 259. Date of Electronic Publication: 2021 Mar 12 (Print Publication: 2021).
DOI:	10.11604/pamj.2021.38.259.15864
Abstrakt:	Introduction: acute diarrhea in children under five years is a public health problem in developing countries and particularly in malaria-endemic areas where both diseases co-exist. The present study examined the etiology of childhood diarrhea and its comorbidity with malaria in a rural area of Burkina Faso. Methods: conventional culture techniques, direct stools examination, and viruses´ detection by rapid tests were performed on the fresh stools and microscopy was used to diagnose malaria. Some risk factors were also assessed. Results: on a total of 191 samples collected, at least one pathogen was identified in 89 cases (46.6%). The proportions of pathogens found on the 89 positive stool samples were parasites 51.69% (46 cases), viruses 39.33% (35 cases), and bacteria 14.61% (13 cases), respectively. The relationship between malaria and infectious diarrhea was significant in viral and parasites causes (p=0.005 and 0.043 respectively). Fever, vomiting and abdominal pain were the major symptoms associated with diarrhea, with 71.51%, 31.72% and 23.66% respectively. The highest viral diarrhea prevalence was reported during the dry season (OR=5.29, 95% CI: 1.74 - 16.07, p=0.001) while parasite diarrhea was more encountered during the rainy season (OR=0.41, 95% CI: 0.33 - 0.87, p=0.011). Conclusion: Giardia spp and rotavirus were the leading cause of acute diarrhea in Nanoro, Burkina Faso with a predominance of rotavirus in children less than 2 years. Parasite and viral diarrhea were the most pathogens associated with malaria. However, the high rate of negative stool samples suggests the need to determine other enteric microorganisms. Competing Interests: The authors declare no competing interests. (Copyright: Palpouguini Lompo et al.)
Databáze:	MEDLINE
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