Bullous pemphigoid-like rash revealing hypereosinophilic syndrome.

Autor: Khallaayoune M; Department of Dermatology, Mohammed V University of Rabat, Rabat, Morocco khallaayounemehdi@gmail.com., Sialiti S; Department of Dermatology, Mohammed V University of Rabat, Rabat, Morocco., Meziane M; Department of Dermatology, Mohammed V University of Rabat, Rabat, Morocco., Senouci K; Department of Dermatology, Mohammed V University of Rabat, Rabat, Morocco.
Jazyk: angličtina
Zdroj: BMJ case reports [BMJ Case Rep] 2021 Jun 08; Vol. 14 (6). Date of Electronic Publication: 2021 Jun 08.
DOI: 10.1136/bcr-2021-242695
Abstrakt: Hypereosinophilic syndrome (HES) is a rare haematologic disorder characterised by unexplained, persistent eosinophilia with organ involvement. We report the case of a 74-year-old patient who presented with a pemphigoid-like bullous rash as the only manifestation of an HES. This report highlights the importance of the dermatological manifestations of this potentially life-threating condition that may initially present as a skin-limited disease. Bullous pemphigoid (BP) is a very common autoimmune blistering dermatosis that may share common clinical and histological features or associate with an HES. HES should be considered when patients diagnosed with BP demonstrate atypical course under corticosteroids and/or recalcitrant blood eosinophilia.
Competing Interests: Competing interests: None declared.
(© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze: MEDLINE