Evaluation of the corneal endothelium by specular microscopy in patients with chronic obstructive pulmonary disease.

Autor: Songur MS; Faculty of Medicine, Department of Ophthalmology, Yozgat Bozok University, Yozgat, Turkey., İntepe YS; Faculty of Medicine, Department of Chest Disease, Yozgat Bozok University, Yozgat, Turkey., Bayhan SA; Faculty of Medicine, Department of Ophthalmology, Yozgat Bozok University, Yozgat, Turkey., Bayhan HA; Faculty of Medicine, Department of Ophthalmology, Yozgat Bozok University, Yozgat, Turkey., Çiftçi B; Faculty of Medicine, Department of Chest Disease, Yozgat Bozok University, Yozgat, Turkey.
Jazyk: angličtina
Zdroj: The clinical respiratory journal [Clin Respir J] 2021 Oct; Vol. 15 (10), pp. 1056-1062. Date of Electronic Publication: 2021 Jun 22.
DOI: 10.1111/crj.13408
Abstrakt: Objective: The objective of this study is to evaluate the corneal endothelium in patients with chronic obstructive pulmonary disease (COPD) using a specular microscope.
Methods: The right eyes of 64 patients with a COPD diagnosis and 65 healthy individuals were evaluated. Cell density (CD) (cell/mm 2 ), corneal thickness (CT) (μ), hexagonal cell ratio (%), and coefficient of variation (cell area standard deviation/mean cell area, μm 2 ) were analyzed by specular microscopy (SM).
Results: The CT was significantly reduced in the COPD group compared with the control group (P = 0.021). Moreover, a significant difference was found between the COPD group and the control group in terms of corneal endothelial CD (P = 0.011), hexagonal cell ratio (P = 0.008), and coefficient of variation (P = 0.012).
Conclusion: The corneal endothelial structure was significantly deteriorated in patients with COPD compared with the control group. SM is a valuable method that could be used in treatment and follow-up of corneal endothelium in patients with COPD.
(© 2021 John Wiley & Sons Ltd.)
Databáze: MEDLINE
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