Nosocomial SARS-CoV-2 transmission in a neonatal unit in Botswana: chronic overcrowding meets a novel pathogen.

Autor:	Nakstad B; Department of Paediatric and Adolescent Health, University of Botswana, Gaborone, Botswana britt.nakstad@medisin.uio.no.; Division of Paediatric and Adolescent Medicine, University of Oslo, Oslo, Norway., Kaang T; Department of Paediatric and Adolescent Health, University of Botswana, Gaborone, Botswana., Gezmu AM; Department of Paediatric and Adolescent Health, University of Botswana, Gaborone, Botswana., Strysko J; Department of Paediatric and Adolescent Health, University of Botswana, Gaborone, Botswana.; Department of Global Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Paediatric Medicine, Botswana-University of Pennsylvania Partnership, Gaborone, Botswana.
Jazyk:	angličtina
Zdroj:	BMJ case reports [BMJ Case Rep] 2021 Jun 07; Vol. 14 (6). Date of Electronic Publication: 2021 Jun 07.
DOI:	10.1136/bcr-2021-242421
Abstrakt:	We describe a cluster of six SARS-CoV-2 infections occurring in a crowded neonatal unit in Botswana, including presumed transmission among mothers, postnatal mother-to-neonate transmission and three neonate-to-healthcare worker transmissions. The affected neonate, born at 25 weeks' gestation weighing 785 g, had a positive SARS-CoV-2 test at 3 weeks of age which coincided with new onset of hypoxaemia and worsening respiratory distress. Because no isolation facility could accommodate both patient and mother, they were separated for 10 days, during which time the patient was switched from breastmilk to formula. Her subsequent clinical course was marked by several weeks of supplemental oxygen, sepsis-like presentations requiring additional antibiotics and bronchopulmonary dysplasia. Despite these complications, adequate growth was achieved likely due to early initiation of nutrition. This nosocomial cluster highlights the vulnerabilities of neonates, caregivers and healthcare workers in an overcrowded environment, and underscores the importance of uninterrupted bonding and breast feeding, even during a pandemic. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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