Prevalence of tuberculosis infection and its relationship to stunting in children (under five years) household contact with new tuberculosis cases.

Autor:	Haerana BT; Department of Epidemiology, Faculty of Public Health, University of Indonesia, Indonesia; Department of Public Health, Universitas Islam Negeri Alauddin Makassar, Indonesia. Electronic address: bs.titihaerana@gmail.com., Prihartono NA; Department of Epidemiology, Faculty of Public Health, University of Indonesia, Indonesia., Riono P; Department of Biostatistics, Faculty of Public Health, University of Indonesia, Indonesia., Djuwita R; Department of Epidemiology, Faculty of Public Health, University of Indonesia, Indonesia., Syarif S; Department of Epidemiology, Faculty of Public Health, University of Indonesia, Indonesia., Hadi EN; Department of Health Education and Behavioral Sciences, University of Indonesia, Indonesia., Kaswandani N; Pediatric Department, RSCM Hospital, Faculty of Medicine, University of Indonesia, Indonesia.
Jazyk:	angličtina
Zdroj:	The Indian journal of tuberculosis [Indian J Tuberc] 2021 Jul; Vol. 68 (3), pp. 350-355. Date of Electronic Publication: 2020 Nov 04.
DOI:	10.1016/j.ijtb.2020.10.011
Abstrakt:	Background: Children who inhabit the same house with tuberculosis (TB) patients are at high risk for infection and illness with TB. Nutritional status (stunting) in children is related to the child's ability to withstand MTB (Mycobacterium Tuberculosis). This study aims to estimated the prevalence of tuberculosis infection and its relationship to stunting in children (under five years) with household contact (HHC) with new TB cases. Methods: A cross-sectional design was implemented. Conducted in July 2018-April 2019 at 13 Public Health Center in Makassar City. The sample size was calculated using one sample situation-about precision formula. Samples were children under five who had contact with new diagnosed TB cases. Tuberculosis infection was measured by TST (tuberculin skin test). Logistic regression with causal model to examine TB infection relationship with stunting and covariate variable, analyzed using Stata/MP 13.0 software. Results: One hundred twenty-six (126) eligible children. Prevalence of tuberculosis infection was 38.10%. Frequency of stunted was 31 children (24.60%). Stunted nutritional status (aPR): 2.36, 95% CI 1.60-3.44), boys (aPR: 1.47, 95% CI 0.96-2.25), not getting BCG immunization (aPR: 1.58, 95%) CI 0.89-2.82), and high contact intensity (aPR: 2.62, 95% CI 1.10-6.22) best predicted the tuberculosis infection in children with TB case household contacts with a model contribution of 64%. Conclusion: Stunted nutritional status (moderate and severe), boys, not getting BCG immunization, and high contact intensity are the determinants of TB infection transmission in children HHC with TB. Children under five years of age who have close contact with TB cases should be targeted for priority interventions to prevent the transmission of TB infection and progressing to TB cases. Competing Interests: Conflicts of interest The authors have none to declare. (Copyright © 2020 Tuberculosis Association of India. Published by Elsevier B.V. All rights reserved.)
Databáze:	MEDLINE
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