Rare cases of rare diseases: Re-examining early 20th century cases of anencephaly from the collection of the Moscow State University, Russia.

Autor: Berezina N; Research Institute and Museum of Anthropology, Lomonosov Moscow State University, Mokhovaya 11, 109029, Moscow, Russia. Electronic address: Berezina.natalia@gmail.com., Buzhilova A; Research Institute and Museum of Anthropology, Lomonosov Moscow State University, Mokhovaya 11, 109029, Moscow, Russia.
Jazyk: angličtina
Zdroj: International journal of paleopathology [Int J Paleopathol] 2021 Sep; Vol. 34, pp. 12-19. Date of Electronic Publication: 2021 Jun 04.
DOI: 10.1016/j.ijpp.2021.05.008
Abstrakt: Objective: Documented cases of anencephaly were used to increase differential criteria of this rare disease.
Material: Two skulls from a 20 th -century documented medical collection at the Moscow State University diagnosed with anencephaly.
Methods: The skulls were evaluated based on macroscopic qualitative and quantitative morphological signs and X-ray analyses.
Results: Metric values and morphological features differ between the two cases of anencephaly noted in the collection and the published data based on normal fetal and neonatal remains.
Conclusions: Analyses of medical collections helps to increase the number of diagnostic criteria for recognition and diagnosis of anencephaly in archaeological skeletons.
Significance: Improvement in the recognition of skeletal alterations associated with anencephaly is key towards improving our understanding of rare diseases in the past.
Limitations: The fragility of skeletal elements of fetal and neonate individuals can complicate thorough analyses.
Suggestions for Further Research: Continue to identify cases of anencephaly cases in medical collections and in archaeological contexts.
(Copyright © 2021 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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