Tolvaptan Response in a Hyponatremic Newborn with Syndrome of Inappropriate Secretion of Antidiuretic Hormone.
| Autor: | Zeybek C; University of Health Sciences, Gulhane School of Medicine, Department of Pediatrics, Division of Pediatric Nephrology, Ankara, Turkey., Bozat AD; University of Health Sciences, Gulhane School of Medicine, Department of Pediatrics, Division of Neonatology, Ankara, Turkey., Calisici E; University of Health Sciences, Gulhane School of Medicine, Department of Pediatrics, Division of Neonatology, Ankara, Turkey., Bolat A; University of Health Sciences, Gulhane School of Medicine, Department of Pediatrics, Ankara, Turkey., Saygili Karagol B; University of Health Sciences, Gulhane School of Medicine, Department of Pediatrics, Division of Neonatology, Ankara, Turkey. |
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| Jazyk: | angličtina |
| Zdroj: | Case reports in pediatrics [Case Rep Pediatr] 2021 May 12; Vol. 2021, pp. 9920817. Date of Electronic Publication: 2021 May 12 (Print Publication: 2021). |
| DOI: | 10.1155/2021/9920817 |
| Abstrakt: | The use of tolvaptan to treat both euvolemic and hypervolemic hyponatremia has rapidly increased in recent years. However, data on its effects on children, especially newborns and infants, are limited. Here, we present a newborn who developed syndrome of inappropriate secretion of antidiuretic hormone following an intracranial hematoma drainage operation who was unresponsive to conventional treatments. The infant was successfully treated with tolvaptan, a competitive inhibitor of the vasopressin V2 receptor. Competing Interests: The authors declare that they have no conflicts of interest. (Copyright © 2021 Cengiz Zeybek et al.) |
| Databáze: | MEDLINE |
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