Epidemiology and characteristics of ischaemic stroke in young adults in Aragon.

Autor:	Tejada Meza H; Unidad de Ictus, Servicio de Neurología, Hospital Universitario Miguel Servet, Zaragoza, Spain; Instituto de Investigación Sanitaria (IIS), Aragón, Zaragoza, Spain. Electronic address: htmeza@gmail.com., Artal Roy J; Unidad de Ictus, Servicio de Neurología, Hospital Universitario Miguel Servet, Zaragoza, Spain., Pérez Lázaro C; Servicio de Neurología, Hospital Clínico Lozano Blesa, Zaragoza, Spain., Bestué Cardiel M; Unidad de Ictus, Servicio de Neurología, Hospital Universitario Miguel Servet, Zaragoza, Spain., Alberti González O; Servicio de Neurología, Hospital San Jorge, Huesca, Spain., Tejero Juste C; Servicio de Neurología, Hospital Clínico Lozano Blesa, Zaragoza, Spain., Hernando Quintana N; Servicio de Neurología, Hospital Obispo Polanco, Teruel, Spain., Jarauta Lahoz L; Servicio de Neurología, Hospital Obispo Polanco, Teruel, Spain., Giménez Muñoz A; Servicio de Neurología, Hospital Royo Villanova, Zaragoza, Spain., Campello Morer I; Servicio de Neurología, Hospital Royo Villanova, Zaragoza, Spain., Fernández Sanz A; Servicio de Neurología, Hospital Universitario Miguel Servet, Zaragoza, Spain., Cruz Velásquez G; Servicio de Neurología, Hospital Universitario Miguel Servet, Zaragoza, Spain., Latorre Jiménez A; Unidad de Ictus, Servicio de Neurología, Hospital Universitario Miguel Servet, Zaragoza, Spain., Vinueza Buitrón P; Servicio de Neurología, Hospital Clínico Lozano Blesa, Zaragoza, Spain., Crespo Burillo JA; Servicio de Neurología, Hospital Ernest Lluch, Calatayud, Zaragoza, Spain., Palacín Larroy M; Servicio de Neurología, Hospital Ernest Lluch, Calatayud, Zaragoza, Spain., Millán García JR; Servicio de Neurología, Hospital de Barbastro, Barbastro, Huesca, Spain., Muñoz Farjas E; Servicio de Neurología, Hospital de Alcañiz, Alcañiz, Teruel, Spain., Oliván Usieto JA; Servicio de Neurología, Hospital de Alcañiz, Alcañiz, Teruel, Spain., Clavo Pérez LM; Servicio de Neurología, Hospital de Barbastro, Barbastro, Huesca, Spain., Marta Moreno J; Unidad de Ictus, Servicio de Neurología, Hospital Universitario Miguel Servet, Zaragoza, Spain; Instituto de Investigación Sanitaria (IIS), Aragón, Zaragoza, Spain.
Jazyk:	angličtina
Zdroj:	Neurologia [Neurologia (Engl Ed)] 2022 Jul-Aug; Vol. 37 (6), pp. 434-440. Date of Electronic Publication: 2021 Jun 04.
DOI:	10.1016/j.nrleng.2019.05.009
Abstrakt:	Introduction: Stroke affects around 15 million people per year, with 10%-15% occurring in individuals under 50 years old (stroke in young adults). The prevalence of different vascular risk factors and healthcare strategies for stroke management vary worldwide, making the epidemiology and specific characteristics of stroke in each region an important area of research. This study aimed to determine the prevalence of different vascular risk factors and the aetiology and characteristics of ischaemic stroke in young adults in the autonomous community of Aragon, Spain. Methods: A cross-sectional, multi-centre study was conducted by the neurology departments of all hospitals in the Aragonese Health Service. We identified all patients aged between 18 and 50 years who were admitted to any of these hospitals with a diagnosis of ischaemic stroke or TIA between January 2005 and December 2015. Data were collected on demographic variables, vascular risk factors, and type of stroke, among other variables. Results: During the study period, 786 patients between 18 and 50 years old were admitted with a diagnosis of ischaemic stroke or TIA to any hospital of Aragon, at a mean annual rate of 12.3 per 100 000 population. The median age was 45 years (IQR: 40-48 years). The most prevalent vascular risk factor was tobacco use, in 404 patients (51.4%). The majority of strokes were of undetermined cause (36.2%), followed by other causes (26.5%). The median NIHSS score was 3.5 (IQR: 2.0-7.0). In total, 211 patients (26.8%) presented TIA. Fifty-nine per cent of the patients admitted with a diagnosis of ischaemic stroke (10.3%) were treated with fibrinolysis. Conclusions: Ischaemic stroke in young adults is not uncommon in Aragon, and is of undetermined aetiology in a considerable number of cases; it is therefore necessary to implement measures to improve study of the condition, to reduce its incidence, and to prevent its recurrence. (Copyright © 2019 Sociedad Española de Neurología. Published by Elsevier España, S.L.U. All rights reserved.)
Databáze:	MEDLINE
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