Prenatal exposure to ambient air pollutants and early infant growth and adiposity in the Southern California Mother's Milk Study.
Autor: | Patterson WB; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA., Glasson J; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA., Naik N; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA., Jones RB; Department of Pediatrics, The Saban Research Institute, Children's Hospital of Los Angeles, University of Southern California, Los Angeles, CA, USA., Berger PK; Department of Pediatrics, The Saban Research Institute, Children's Hospital of Los Angeles, University of Southern California, Los Angeles, CA, USA., Plows JF; Department of Pediatrics, The Saban Research Institute, Children's Hospital of Los Angeles, University of Southern California, Los Angeles, CA, USA., Minor HA; Sonoma Technology, Inc, Petaluma, CA, USA., Lurmann F; Sonoma Technology, Inc, Petaluma, CA, USA., Goran MI; Department of Pediatrics, The Saban Research Institute, Children's Hospital of Los Angeles, University of Southern California, Los Angeles, CA, USA., Alderete TL; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA. tanya.alderete@colorado.edu. |
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Jazyk: | angličtina |
Zdroj: | Environmental health : a global access science source [Environ Health] 2021 Jun 05; Vol. 20 (1), pp. 67. Date of Electronic Publication: 2021 Jun 05. |
DOI: | 10.1186/s12940-021-00753-8 |
Abstrakt: | Background: Prior epidemiological and animal work has linked in utero exposure to ambient air pollutants (AAP) with accelerated postnatal weight gain, which is predictive of increased cardiometabolic risk factors in childhood and adolescence. However, few studies have assessed changes in infant body composition or multiple pollutant exposures. Therefore, the objective of this study was to examine relationships between prenatal residential AAP exposure with infant growth and adiposity. Methods: Residential exposure to AAP (particulate matter < 2.5 and 10 microns in aerodynamic diameter [PM Results: NO Conclusion: Prenatal AAP exposure was associated with increased weight gain and anthropometric measures from 1-to-6 months of life among Hispanic infants. Sex-specific associations suggest differential consequences of in utero oxidative stress. These results indicate that prenatal AAP exposure may alter infant growth, which has potential to increase childhood obesity risk. |
Databáze: | MEDLINE |
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