Sweet Dre-ams about intersectional genetics.

Autor: Woods JP; Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA., Srinivasan RS; Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA., Olson LE; Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA. Electronic address: lorin-olson@omrf.org.
Jazyk: angličtina
Zdroj: Cell stem cell [Cell Stem Cell] 2021 Jun 03; Vol. 28 (6), pp. 989-990.
DOI: 10.1016/j.stem.2021.05.005
Abstrakt: Specific cell targeting with one site-specific recombinase is challenging. In this issue of Cell Stem Cell, Han et al. (2021) released a collection of Dre drivers and demonstrate how two recombinases can be combined to improve the cell specificity of lineage tracing and gene inactivation in mice.
(Copyright © 2021 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE